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Immediate Effect of Electrical Noise Stimulation on Neuromuscular Adaptation of Balance

Immediate Effect of Electrical Noise Stimulation on Neuromuscular Adaptation During Single-Leg Stance in Healthy Young

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05570890
Enrollment
20
Registered
2022-10-07
Start date
2022-04-29
Completion date
2023-01-31
Last updated
2022-10-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Balanced, Electroencephalography, Electromyography

Keywords

Center of pressure, Electroencephalography, Electromyography, H reflex, Electrical noise stimulation

Brief summary

Noise stimulation had an immediate effect on improving balance control. The present study aimed to clarify the immediate neuromuscular adaptation induced by noise stimulation and find the correlation between neuromuscular adaptation and functional performance.

Detailed description

The mechanism behind noise stimulation is called Stochastic Resonance which improves the detectivity of sensory input with the presence of noise, making sub-sensory threshold input detectable. Noise stimulation had been proved to improve postural control, Ia afferent sensitivity, and muscle activity of the tibialis anterior. With this evidence of the effect of noise stimulation on balance enhancement, the neuromuscular adaptation induced by noise stimulation has not been researched yet. Therefore, the present study aims to clarify the immediate effect of noise on neuromuscular regulation during postural control.

Interventions

DEVICEelectrical noise stimulation

The intensity of electrical noise stimulation will be set at 90% of the sensory threshold of each participant.

DEVICESham stimulation

Participants will not receive stimulation.

DEVICEFoam

The foam will be used to make an unstable surface.

Sponsors

National Yang Ming Chiao Tung University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
SINGLE (Subject)

Masking description

The stimulation intensity is set under the sensory threshold, therefore participants will be masked in the study.

Eligibility

Sex/Gender
ALL
Age
20 Years to 40 Years
Healthy volunteers
Yes

Inclusion criteria

* age between 20 and 40 years old * without ankle injury history in 1 year * without musculoskeletal or neurological diseases that would affect balance performance * without visual impairment (except vision correction or no visual problems) * without vestibular impairment.

Exclusion criteria

* subject who cannot tolerate the cutaneous electrical stimulation to induce H reflex * single-leg stance (SLS) without support is shorter than 80 secs

Design outcomes

Primary

MeasureTime frameDescription
Mean sway path of the center of pressure40 seconds under each conditionThe mean sway path in mm will represent balance performance
Mean sway velocity of the center of pressure40 seconds under each conditionThe mean sway velocity in mm/sec will represent balance performance
Cortical excitability40 seconds under each conditionPower spectrum density of EEG will calculated for representing cortical excitability.
Spinal reflex excitability40 seconds under each conditionH reflex amplitude will represent the excitability of peripheral control from spinal level nerve system.
Co-activation index40 seconds after each conditionCo-activation index will be calculated by EMG activity of Tibialis Anterior and Soleus muscle to represent the muscle activity.

Countries

Taiwan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026