Gastric Residual Volume
Conditions
Brief summary
General Anesthesia requires preoperative fasting according to specific instructions. Regarding Fasting Guidelines, The American Society of Anesthesiologists (ASA) recommends patients to fast from fatty food or meat eight hours prior to surgery, non-human milk or light meal for six hours prior, breast milk for four hours prior, and clear liquids including water, pulp-free juice, and tea without milk for two hours prior to the anesthetic. ASA fasting guidelines application represents the primary method to avoid aspiration as it ensures that stomach is empty before induction of anesthesia. These guidelines cannot be applied on all cases as in urgent or emergent situations or in morbidities associated with delayed gastric emptying, like Diabetes mellitus and some neurological disorders (
Interventions
DRUGDomperidone
ultrasound guieded assesment of gastric residual volume will be done 2 h after oral injestion of domperidone tablet
DRUGFolic acid
ultrasound guieded assesment of gastric residual volume will be done 2 h after oral injestion of folic acid tablet
Sponsors
Ain Shams University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* Patients of both sexes * aged between 18-65 years * who are categorized by ASA physical status as I or II * undergoing elective surgeries under general anesthesia
Exclusion criteria
* Patients with known or suspected delayed gastric emptying (e.g. Diabetes mellitus) -psychiatric disorders * hypersensitivity to the study medications * peoples undergoing surgeries that associated with high incidence of Post operative nausea and vomiting (PONV) (e.g. Cholecystectomy, gynecological, ophthalmological, otorhinolaryngological, and laparoscopic surgeries).
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| assess the effect of oral Domperidone preoperatively on gastric residual volume by ultrasound for patients undergoing elective surgeries under general anesthesia | first 2 hours preoperative | patients will receive 400 ml of apple juice as a clear fluid, two hours preoperatively, and oral Domperidone tab or placebo tab |
Countries
Egypt
Outcome results
None listed