Circadian Rhythm Sleep Disorder
Conditions
Keywords
Chonobiology, Cognitive performance, Insomnia, Shift work, Sleepiness
Brief summary
Poor sleep is closely related to circadian misalignment; shift workers often experience shift work disorder characterized by excessive sleepiness and recurrent shift work schedules-associated insomnia. This study aims to examine the effects of a program of chronobiology-guided lifestyle interventions (CGLI) on insomnia severity, cognitive performance (psychomotor vigilance and processing speed), and sleepiness in female nurses undertaking rotating-shift work.
Detailed description
This study will use a parallel-group, randomized, assessor-blind, wait-list controlled design to determine the effects of a program of multimodal lifestyle interventions based on chronobiology, consisting of timed bright light exposure, meal timing manipulations, and sleep hygiene education on insomnia severity, cognitive performance (psychomotor vigilance and processing speed), and sleepiness in female nurses undertaking rotating-shift work.
Interventions
BEHAVIORALChronobiology-guided lifestyle interventions
1\) timed bright light exposure using blue-enriched white light glasses, 2) recommendations for meal timing, and 3) sleep hygiene education
Sponsors
Taipei Medical University
Ministry of Science and Technology, Taiwan
Taipei Veterans General Hospital, Taiwan
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
DOUBLE (Subject, Outcomes Assessor)
Eligibility
Sex/Gender
FEMALE
Age
20 Years to 60 Years
Healthy volunteers
Yes
Inclusion criteria
1. Females aged 20 to 60 who work full time as a nurse and work a 3-shift rotation, including day shifts, evening shifts, and night shifts in the most recent 6 months. 2. Participants must complain of insomnia symptoms and/or sleepiness in relation to shift work schedule for at least 3 months. 3. Participants must have10 workdays (evening or night shift) within a 14-day period during the study period.
Exclusion criteria
1. Active physical diseases. 2. Moderate to severe psychopathology. 3. Medications or treatments that may affect sleep. 4. Pregnant or breastfeeding. 5. Participants must be free of ophthalmic pathology, eye surgery, and diseases affecting the retina or taking photosensitizing drugs. 6. Participants who have been diagnosed with sleep-disordered breathing will be excluded. Sleep-disordered breathing such as obstructive sleep apnea (OSA) will be screened using the snoring, tiredness, observed apnea, high BP, BMI, age, neck circumference, and male gender (STOP-BANG) questionnaire.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| insomnia severity | Through study completion, an average of 14days | The Insomnia Severity Index will be used to determine the severity of insomnia. The Insomnia Severity Index with a total score ranging from 0 to 28. A higher Insomnia Severity Index score indicates more severe insomnia. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| The neurobehavioral function of cognitive performance | Through study completion, an average of 14 days | The neurobehavioral function will be evaluated using the Walter Reed Psychomotor Vigilance Test (PVT), a portable reaction-time test based on the Dinges and Powell digital test. The PVT will be testing a 5-min test with responses to randomly spaced stimuli per test. |
| The processing speed of cognitive performance | Through study completion, an average of 14 days | A Tablet-based Symbol Digit Modalities Test (T-SDMT) will be used to test processing speed. |
| The sleepiness at work | Through study completion, an average of 14 days | The Karolinska Sleepiness Scale (KSS) will be used to measure sleepiness at work. It is on a scale of 1 to 9. A higher score is more sleepy. |
Countries
Taiwan
Contacts
Primary ContactPei-Shan Tsai, Professor
Backup ContactShan-Ying Wu, Master
Outcome results
None listed