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Comparison of Effectiveness of Pre-cooling With Ethyl Chloride Versus Honey

Comparison of Effectiveness of Pre-cooling With Ethyl Chloride Versus Honey in Alleviating Intra-oral Injection Pain in Adult Patients

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05568563
Enrollment
90
Registered
2022-10-05
Start date
2022-08-01
Completion date
2022-09-30
Last updated
2022-11-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Irreversible Pulpitis

Brief summary

Comparing Pre-cooling with Ethyl Chloride versus Honey in Alleviating Intra-oral injection pain in Adult patients

Interventions

Ethyl chloride is an agent that is widely used in dental practice as the standard modality for pulp vitality tests .

OTHERHoney

Honey is a natural dietary product

Sponsors

Altamash Institute of Dental Medicine
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)

Eligibility

Sex/Gender
ALL
Age
18 Years to 50 Years
Healthy volunteers
Yes

Inclusion criteria

* No medical history * Patients suffering from Symptomatic Irreversible Pulpitis requiring buccal infiltration

Exclusion criteria

* Patients having any medical conditions considered to affect patient safety or the quality of the study * if they had any known hypersensitivity to local anaesthetics of amide type or any of the other contents in the substance used

Design outcomes

Primary

MeasureTime frameDescription
To alleviate dental injection painimmediately after completion of administration of oral local anesthetic infiltration within 60 secondsPost administration of oral local anesthetic infiltration pain will be measured by using Visual Analogue Scale(VAS) which is an 10-point scale from 0-10 where 0 represents no pain and 10 represents the worst pain measured

Countries

Pakistan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026