COVID-19-Associated Encephalitis, Long COVID
Conditions
Keywords
pediatric neurology, psychiatric evaluation, Long COVID syndrome, magnetic resonance image
Brief summary
We enroll pediatric patients who were diagnosed COVID-19 for main observation target. We will perform brain MRI and neuropsychiatric evaluation 4-6 months after COVID-19 diagnosed. We also enroll healthy age- and gender-matched participant for cross-over comparison. We will perform same evaluation process one year later for longitudinal evaluation
Interventions
DIAGNOSTIC_TESTBrain MRI
Brain MRI including diffusion spectrum image, and functional MRI Interview with questionnaires for neuropsychiatric evaluation Near infrared spectroscopy and resting-state connectivity evaluation
Sponsors
National Taiwan University Hospital
Study design
Observational model
CASE_CROSSOVER
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
6 Years to 18 Years
Healthy volunteers
Yes
Inclusion criteria
* Age 6-18 years old * Has been diagnosed COVID-19 before
Exclusion criteria
* History of neuropsychiatric disorders * Have some device not allowed for MRI
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Difference between COVID and healthy group | 1 years after enrollment for primary evaluation | The neuroimage difference between COVID and healthy group and the correlation with neuropsychiatric evaluation |
Countries
Taiwan
Contacts
Primary ContactWang-Tso Lee, PHD
Outcome results
None listed