Treatment of Moderate FMR During AVR

Surgical Treatment of Aortic Valve Disease With Moderate Functional Mitral Regurgitation

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05566340

Enrollment

154

Registered

2022-10-04

Start date

2022-10-31

Completion date

2023-12-31

Last updated

2022-10-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Functional Mitral Regurgitation

Keywords

functional mitral regurgitation, aortic valve replacement, mitral valve repair

Brief summary

Debates exist on the treatment of moderate functional mitral regurgitation (FMR) in patients undergoing aortic valve replacement (AVR) for aortic valve disease. This study aims to evaluate the left ventricular function, which was evaluated through global longitudinal strain, after isolated AVR and AVR + mitral valve repair (MVr) in this group of patients.

Interventions

PROCEDUREmitral valve repair

Repair of mitral valve concomitant to aortic valve replacement.

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

1. Patients who received AVR (with or without concomitant MVr) from two center (Fuwai Yunnan Cardiovascular Hospital and Fuwai Hospital, Chinese Academy of Medical Sciences). 2. Age more than 18 years.

Exclusion criteria

1. Those with a history of rheumatic valvular disease or infective endocarditis. 2. Primary mitral valve lesions. 3. Patients receiving mitral valve replacement. 4. Patient who refuse to participate in this study, or cannot complete 6-month follow-up after surgery. 5. Age \< 18 years.

Design outcomes

Primary

Measure	Time frame	Description
left ventricular global longitudinal strain	10/10/2022-10/10/2023	The change of left ventricular global longitudinal strain compared to before surgery

Contacts

Primary ContactXieraili Tiemuerniyazi

tiemuernyz@mail2.sysu.edu.cn+86-18814115887

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026