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CARG, VES13, G8 Scales in Predicting Drug Toxicity in Patients Receiving Nivolumab

CARG, VES13, G8 Scales in Predicting Drug Toxicity in Patients Receiving Nivolumab

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05564923
Enrollment
100
Registered
2022-10-04
Start date
2022-09-02
Completion date
2023-08-17
Last updated
2022-10-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nivolumab Related Toxicity

Brief summary

The Geriatric 8 (G8), Vulnerable Elders Survey (VES-13), and Cancer and Aging Research Group (CARG) questionnaires are among the main tests whose purpose is to predict the risk of chemotherapy-induced toxicity (CRT) and allow treatment. Investigators aimed to investigate the effect of using the G8, VES13, and CARG scales in the geriatric age group in cancer patients receiving nivolumab treatment in predicting side effects.

Detailed description

Investigator aimed to examine whether the G8, VES13, and CARG scales can shed light on clinicians in predicting side effects during the use of nivolumab in geriatric cancer patients. In the chemotherapy unit, demographic information, diagnosis date of the disease, previous treatments, comorbidities, and CARG, VES13, and G8 questionnaires will be recorded face-to-face to the patients who meet the study criteria. In addition, routine hemogram and biochemistry tests, which were requested by the patient's follow-up physician before Nivolumab treatment and which will be requested by the patient's own physician during follow-up visits, will be recorded prospectively. Side effects that may occur during nivolumab treatment will be pursued at each visit. CTCA v.6. will be used for grading. inclusion criteria 1-Advanced cancer patients whose nivolumab treatment was started by the physician followed up (independent of diagnosis) 2-60 years and over, 3-ECOG performance score 0-1 4-Patients who signed the informed consent form exclusion criteria 1. Under 60 years old 2. Ecog score \>1

Interventions

DRUGthere is no intervention

there is no intervention

Sponsors

Namik Kemal University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
60 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Advanced stage cancer patients who have been treated with nivolumab * be over 60 years old

Exclusion criteria

* be under the age of 60

Design outcomes

Primary

MeasureTime frameDescription
grade 3-4 nivolumab toxicityone year from first patient enrolledgrading will be made according to the CTCA V.6

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026