Acupuncture, Acute Ischemic Stroke, Mechanical Thrombectomy
Conditions
Brief summary
To evaluate the efficacy and safety of head acupuncture combined with endovascular therapy for cerebral infarction compared with endovascular therapy alone
Detailed description
Control group: Mechanical thrombectomy followed by the guideline recommended treatment for acute ischemic stroke; Experimental group: After mechanical thrombectomy, head acupuncture and the treatment regimen recommended by the guideline for acute ischemic stroke were administered
Interventions
OTHERScalp Acupuncture
mplementation plan of head needle: The middle frontal line (MS1), the middle parietal line (MS5) and the back parietal and temporal oblique line (MS7) in the International Standardization Program for the Name of the first needle Point in 1989 were selected, and the needles were inserted along the shape of each section. One needle was inserted into the middle frontal line and the middle parietal line, and two needles were inserted into the back parietal and temporal oblique line. The KWD-808I pulse electrotherapy instrument produced by Changzhou Wujin Great Wall Medical Equipment Co., Ltd. is used on the needle handle after lifting, inserting and twisting. The continuous waveform was used, the voltage was 2-4 V, the frequency was 60-80 times /min, the intensity was tolerated by the patient, the needle was kept for 30min, and the treatment was performed once a day.
OTHERThe treatment recommended in the guidelines for acute ischemic stroke was administered
The treatment recommended in the guidelines for acute ischemic stroke was administered
Sponsors
Xi'an No.3 Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 100 Years
Healthy volunteers
No
Inclusion criteria
* Age ≥18 years; * Patients with acute ischemic stroke who received endovascular treatment within 24 hours of onset; * 6 \< NIHSS ≤25; * ASPECT score ≥6 points; * Signed Informed consent.
Exclusion criteria
* CT or brain MRI confirmed intracranial tumor and intracranial hemorrhage; * Contraindications of contrast media; * Dementia or mental illness，unable to cooperate with treatment and follow-up; * The expected survival time was less than 3 months; * Women who are pregnant, planning to become pregnant or breastfeeding; * Currently participating in other clinical trials.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Ratio of Modified rankin scale (mRS) score ≤2 | 90 days after onset | The modified rankin Scale (mRS) score ≤2 indicates that the patient has the ability to live independently. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| National Institute of Health stroke scale(NIHSS) score | 10 days after onset | NIHSS scores range from 0 to 42, with higher scores indicating more severe nerve damage. |
| Modified rankin scale (mRS) score | 90 days after onset | Modified rankin scale (mRS) Score is used to measure the neurological function recovery status of patients after stroke, and its score ranges from 0 to 6 |
| Incidence of cerebral hemorrhage | 7 days after randomization | No hemorrhage was found on the first head CT/MRI after cerebral infarction, but intracranial hemorrhage was found on the second head CT/MRI |
Countries
China
Contacts
Primary ContactShilin L i, Doctor
Backup ContactMingze Chang, Doctor
Outcome results
None listed