Myotonic Dystrophy Type 1 (DM1)
Conditions
Brief summary
Myotonic Dystrophy type 1 (DM1) is a genetic multisystem disease causing muscle weakness and myotonia. As a result, upper limb function might become impaired. There are little research regarding rehabilitation and exercise for upper limb function in DM1. It is known from research on lower limb function in DM1 and other muscular dystrophies, that there are possibilities to improve function also in these deteriorating diseases. In this single subject experimental design study, 6-10 adults with DM1, who are at an inpatient rehabilitation center, will get intensive, but personally adapted senso- and robot assisted rehabilitation for arm- and hand function with Tyromotion Amadeo and Armeo Senso. These devices have previously been used in rehabilitation research for other neurological conditions. The participants will be followed up, and evaluated at a weekly basis, using video consultations. Fine motor skill dexterity test (9HPT) and the Nut and Bolt test will be used, and active range of motion (ROM) and muscle strenght and movement of upper limb will be measured. Furthermore, patient reported outcome measures (PROMS) on hand impairment and myotonia will be used, all with purpose to evaluate upper limb function.
Interventions
DEVICETyromotion Amadeo and Armeo Senso
Robot assisted rehabilitation for arm- and hand function with Tyromotion Amadeo and Armeo Senso
Sponsors
Oslo University Hospital
Vikersund Rehabilitation Center
University of Oslo
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Intervention model description
Single subject experimental design (SSED) study
Eligibility
Sex/Gender
ALL
Age
18 Years to 99 Years
Healthy volunteers
No
Inclusion criteria
* Granted rehabilitation at Vikersund Rehabilitation center Genetical confirmed myotonic dystrophy diagnosis MIRS score between 2-5
Exclusion criteria
* MIRS score on 1 Reduced Cognitive function and unable to participate in technological rehabilitation and digital evaluation
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Fine motor skill dexterity test, 9 hole peg test (9HPT) | 1-3 minutes | Motor skill test |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Range of motion (ROM) | 5-10 minutes | Measure of ROM in upper limb joints |
| Nut and Bolt test | 5 minutes | Motor skill test |
| Hand strength | 5 minutes | Measured by Jamar digital dynamometer |
| Pinch Gauge | 5 minutes | Finger strength measures by Jamar digital pinch gauge |
Other
| Measure | Time frame | Description |
|---|---|---|
| Abilhand | 5 minutes | Patient reported outcome measure, measure of manual ability for adults with upper limb impairment |
| Myotonia behavior scale | 1-5 minutes | Patient reported outcome measure |
Countries
Norway
Outcome results
None listed