Multiple Sclerosis
Conditions
Keywords
Vojta Therapy, Bobath Therapy
Brief summary
Multiple sclerosis is the most common disabling neurological disease in young adults. Inflammation, demyelination, neurodegeneration, gliosis and repair processes are involved in its process, which are responsible for the heterogeneity and individual variability in the expression of the disease, the prognosis and the response to treatment. Clinically, MS manifests itself with the following symptoms: sensory focus, motor focus, spasticity, balance disorders, visual disturbances such as loss of vision or double vision or sphincter dysfunction. The main subtypes of MS are relapsing-remitting, secondary progressive, primary progressive, and progressive relapsing. Clinically, RRMS presents the initial inflammatory phase, characterized by reversible flares with neurological dysfunction, followed by periods of remission. Approximately 40-50% of these patients progress to SPMS, where the disease gradually progresses from intermittent flare-ups to steadily progressive worsening, resulting in permanent disability due to massive axonal loss. PPMS is the most severe subtype, affecting approximately 10% of all cases, and manifesting as progressive degeneration without any remission.
Detailed description
From the field of Physiotherapy, one of the main tools for the treatment of MS is physical exercise. Numerous studies show that exercising is safe and beneficial in people with MS, as long as it is done correctly and supervised by health professionals. Physical exercise is considered an important part of symptomatic and supportive treatment for people with MS, since it induces improvement of physiological functions affected by lack of physical activity and helps to manage some symptoms, such as spasticity, fatigue and lack of balance There are therapies within Physiotherapy that help treat MS such as the Vojta Method and the Bobath Method.
Interventions
Our study will be a Randomized Clinical Trial. It will be held at the Aymara Abreu Physiotherapy Clinic center, with a maximum duration of 1 year. It will consist of two parts. In the first stage of the treatment we will carry out an initial assessment, and in the second stage a final assessment. After that, the corresponding data analysis will be carried out.
Sponsors
Study design
Masking description
Our population will be subjects diagnosed with MS. Prior to the study, the informed consent will be presented to the subjects. Said confidentiality will be contemplated in Organic Law 15/99 of December 13 on the Protection of personal data.
Intervention model description
Our study will be a Randomized Clinical Trial. It will be held at the Aymara Abreu Physiotherapy Clinic center, with a maximum duration of 1 year. It will consist of two parts. In the first stage of the treatment we will carry out an initial assessment, and in the second stage a final assessment. After that, the corresponding data analysis will be carried out.
Eligibility
Inclusion criteria
* Persons with MS who have signed the informed consent. * Persons of both sexes. * Ages between 20 and 65 years. * Subjects of both sexes diagnosed with multiple sclerosis on the EDSS (Expanded Disability Status Scale).
Exclusion criteria
* Persons with multiple sclerosis with EDSS scale score equal to or greater than 7.0. * Occurrence of a flare during the period of the patient's participation in the study. * Pregnant women. * Oncology patients. * Non-acceptance and non-signing of informed consent. * Refusal to participate in the study. * Patients with severe cognitive impairment that does not allow them to understand the development of the study. * Patients with cardiovascular instability. * Patients who do not complete at least 75% of the scheduled sessions. Patients who do not present any of the contraindications contemplated for Vojta therapy.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Respiratory function | 5 minutes | Respiratory function will be assessed with a pressure manometer to measure peak inspiratory pressure. |
| Spasticity | 10 minutes | Spasticity will be measured using the Tardieu scale. |
| Balance | 10 minutes | The balance will be measured through the Berg scale. |
| Age | 1 minutes | — |
| Time reaction | 5 minutes | Reaction time will be measured by the Cognifit test |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Myelin | 15 minutes | Myelin will be me measured trough the tear duct whit phospholipid test strips |