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Youth Nominated Support Team

Youth Nominated Support Team for Suicidal Adolescents at Clinical High Risk for Psychosis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05558332
Acronym
YST
Enrollment
70
Registered
2022-09-28
Start date
2025-03-12
Completion date
2026-11-01
Last updated
2026-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Family Members, Health Care Utilization, Psychosis, Suicide

Brief summary

This study aims to adapt the current Youth-Nominated Support Team (YST) manual used to treat suicide risk for people at clinical high risk for psychosis.

Detailed description

Psychotic disorders are characterized by high rates of suicidal ideation and behavior, and the risk for suicide appears to be greatest during the earliest stages of psychosis. A recent meta-analysis showed that the majority of youth at clinical high-risk (CHR) for psychosis experience suicidal ideation, and that approximately one in five make at least one suicide attempt. There are, however, no suicide prevention interventions specifically tailored to the needs of transition-aged youth at CHR, and no current best practice guidelines for how to respond to suicide risk in this population. The Youth-Nominated Support Team (YST) intervention has recently been shown to reduce mortality among adolescents and is potentially highly adaptable within the context of existing CHR services. YST is intended as an adjunctive treatment and is primarily delivered towards support persons rather than the youth themselves, and therefore would not interfere or overlap with the already extensive direct services provided in CHR treatment settings. The proposed project intends to adapt the YST intervention for CHR populations. Specifically, the investigators aim to: (1) adapt YST for CHR based on stakeholder input (i.e., clients, family/friends, clinicians) and to develop a new treatment manual and submit an additional IRB to cover the next two aims -- (2) to implement YST in a single CHR clinic and to revise the intervention based on input from clients, providers, and support person and (3) conduct a pilot randomized clinical trial at four SAMHSA funded CHR sites to test the efficacy of the adapted YST intervention and to identify underlying mechanisms of change. The investigators hypothesize that the revised intervention will be superior to existing practice for the reduction of suicidal ideation and behavior.

Interventions

BEHAVIORALYouth-Nominated Support Teams for CHR

Intervention for adolescents aimed at preventing, reducing, and/or managing suicidal thoughts and behaviors. YST-CHR is an "add on" to the treatment and therapy they are already receiving. Study clinicians will administer the adapted YST treatment manual to participants, aimed at improving suicidal risk.

Sponsors

University of California, Irvine
Lead SponsorOTHER
University of Maryland, Baltimore County
CollaboratorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Intervention model description

One group will recieve the adapted YST treatment (YST-CHR) and the other group will receive treatment as usual. Participants receiving the existing treatment will be offered YST-CHR after the study is over if appropriate

Eligibility

Sex/Gender
ALL
Age
12 Years to 25 Years
Healthy volunteers
No

Inclusion criteria

* A person with suicidal ideation in the past 3 months or suicidal attempt in the past year * A person who is receiving or has received treatment for psychosis risk symptoms * Between the ages of 12-25

Exclusion criteria

* Cannot have participated in the first 2 phases of the study (focus groups and adaption of the YST-CHR manual)

Design outcomes

Primary

MeasureTime frameDescription
Social Connectedness3-months after interventionConnectedness will be measured with the 5-item Thwarted Belongingness subscale of the Interpersonal Needs Questionnaire. Scores range from 15-105 and a higher score indicates lower social connectedness.
Increased Hope3-months after interventionHopelessness will be measured with the 4-item Beck Hopelessness Scale (BHS). Hopelessness may be a very sensitive indicator of subsequent suicide risk, particularly among youth with psychosis. The total BHS score is a sum of item responses from 0 to 20 such that higher scores reflect higher levels of hopelessness. Scores greater than 14 identify severe hopelessness.
Treatment Engagement3-months after interventionThis will be measured using clinic records of appointment attendance to determine number of therapy sessions attended.

Secondary

MeasureTime frameDescription
Severity and Intensity of Suicidal IdeationBaseline, 6 weeks after intervention, and 3 months after interventionThis will be drawn from the Columbia Suicide Severity Rating Scale (C-SSRS). The scores range from 0 to 25. Higher scores indicate higher suicide risk symptoms.

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Apr 15, 2026