Periodontitis
Conditions
Keywords
Periodontitis
Brief summary
In light of the controversy that are already approved but that however still exists regarding the efficacy and influence of the protocols for the management of periodontitis, the aim of this study was to evaluate, at 6 months follow-up, the post-treatment clinical parameters and immunological and gingival microbial profiles in patients with periodontitis, treated by either SRP in addition to full mouth periodontal debridement.
Detailed description
This trial was conducted in accordance with the World Medical Association's Declaration of Helsinki of 1975, and reviewed in 2008. Patients were enrolled from January 2020 to December 2022. The local ethical committee of approved the study protocol (125/PO) and each patient was carefully informed about the possible inherent risks of the study and provided their informed written consent 88 patients, aged 27 to 65 (mean age 57) were assessed for eligibility. In all subjects, subgingival plaque will acquired from 4 separate proximal periodontal sites.
Interventions
PROCEDUREScaling and root planing
Full mouth or quadrant SRP
Sponsors
University of Catania
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Investigator)
Masking description
Both participants and clinicians were blinded to group and treatment assignment
Intervention model description
Patients undergo non-surgical quadrant scaling and root planing
Eligibility
Sex/Gender
ALL
Age
25 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
1. good condition of general health, 2. a minimum of 2 teeth for each quadrant with a Pocket Depth (PD) ranging from 4-6 mm, 3. no involvement of the furcation, 4. a minimum of a six teeth per quadrant, respectively.
Exclusion criteria
1. periodontal therapy during the last 12 months, 2. assumption of antibiotics during the last 6 months, 3. pregnancy, 4. any systemic condition which might affect the effects of the study treatment, 5. previous or current radiation or immunosuppressive therapies, 6. use of mouthwash containing antimicrobials during the previous 3 months, 7. no use of hormonal contraceptives, 8. medication by anti-inflammatory and immunosuppressive drugs, 9. previous history of hard-drinking, 10. smoking, 11. class II and III tooth mobility.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Probing depth changes | 6 months | Measurment of Probing Depth changes in millimeters |
Countries
Italy
Outcome results
None listed