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Reducing Unnecessary Antibiotic Prescriptions in Primary Healthcare in Saskatchewan by Identifying High Prescribers

Reducing Unnecessary Antibiotic Prescriptions in Primary Healthcare in Saskatchewan by Identifying High Prescribers

Status
Withdrawn
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05557214
Enrollment
0
Registered
2022-09-27
Start date
2023-05-31
Completion date
2024-05-31
Last updated
2023-04-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Upper Respiratory Tract Infections

Keywords

audit and feedback, antimicrobials, primary healthcare

Brief summary

Approximately 90% of antibiotics are prescribed in primary healthcare (PHC) in Canada (Public Health Agency of Canada, 2020), making this an important sector for antimicrobial stewardship. Upper respiratory tract infections (URTIs) represent a common indication in PHC for which antibiotics are often prescribed unnecessarily (Leis et al, 2020; Schwartz et al., 2020). Reducing unnecessary antibiotic treatment in this sector is a vital part of contributing to minimizing the global burden of antibiotic resistance. The goal of this research project is to reduce the number of antibiotic prescriptions among family physicians identified as high prescribers in Saskatchewan. To achieve this, the investigators will send letters to the top 25th percentile of high prescribers in PHC. The letters will contain data indicating the prescribers high antimicrobial usage as well as guidance for reducing unnecessary prescriptions and promoting appropriate lengths of prescriptions for upper respiratory tract infections.

Interventions

BEHAVIORALAudit and Feedback Letter

Physicians in the Audit and Feedback Letter Arm will receive an initial letter indicating their high prescriber status with guidance on reducing unnecessary antimicrobial use. They will also receive a follow-up letter at the 6 month mark indicating any change in prescribing habits. There will be a study closure letter mailed at the 12 month mark.

Sponsors

Saskatchewan Health Authority - Regina Area
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE

Eligibility

Sex/Gender
ALL
Healthy volunteers
Yes

Inclusion criteria

* must be a practicing family physician in Saskatchewan * top 25th percentile of antimicrobial prescribers

Exclusion criteria

* fewer than 12 months of historical prescribing data available

Design outcomes

Primary

MeasureTime frameDescription
Total Antibiotic Prescriptions12 monthsTotal number of antibiotic prescriptions compared to covariate-adjusted baseline number of prescriptions prior to the intervention.

Secondary

MeasureTime frameDescription
Total Prolonged-Duration Prescription12 monthsNumber of prescriptions longer than 7 days.
Total Days of Therapy12 monthsNumber of days of therapy of antimicrobials for each provider.
Antibiotic Cost12 monthsTotal cost of prescribed antibiotics.
Total Specific Antibiotic Prescriptions12 monthsNumber of prescriptions for specific antibiotics.

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026