BMP-2 and ALP Levels Following Laser Therapy With Scaling and Root Planing in Periodontitis- RCT.

Assessment of BMP-2 and ALP Levels Following Laser Therapy as an Adjunct to Scaling and Root Planing for Treatment of Periodontitis- A Randomized Clinical Trial.

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT05555420

Enrollment

Registered

2022-09-26

Start date

2022-11-01

Completion date

2023-12-01

Last updated

2022-09-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Periodontitis, Laser

Brief summary

Patients with periodontitis will be treated by either SRP only or SRP in combination with laser. Samples from GCF will be collected immediately after treatment and at 3 months follow-up time. Levels of BMP-2 and ALP will be assessed at these time points. Statistical analysis to compare the results will be performed.

Interventions

DEVICESRP+Laser

Non-surgical periodontal therapy in combination with Laser

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* Periodontitis

Exclusion criteria

* Uncontrolled medical condition

Design outcomes

Primary

Measure	Time frame	Description
Amount of attachment gain	3 months	Described in mm

Secondary

Measure	Time frame	Description
Level of BMP-2 in GCF	3 months	ELISA test
Level of ALP in GCF	3 months	Colorimetry

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026