24-hour Urinary Electrolyte Excretion in Chronic Kidney Disease

24-hour Urinary Electrolyte Excretion and Renal Prognosis in Chronic Kidney Disease：a Retrospective Cohort Study

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05550467

Enrollment

10000

Registered

2022-09-22

Start date

2014-01-01

Completion date

2022-07-31

Last updated

2022-09-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Kidney Diseases, Electrolyte Imbalance

Brief summary

Association between excretion pattern and development trajectory of urinary electrolytes (urine sodium, urine potassium, urine chlorine, urine magnesium, urine calcium, urine phosphorus, urine creatinine, urea, uric acid, urine glucose, urine protein, urine retinol) and adverse prognosis in patients with chronic kidney disease

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 100 Years

Healthy volunteers

Inclusion criteria

* Our study is a retrospective cohort study. The study included patients with adult（Age≥18years）CKD who were hospitalized in the Department of Nephrology, First Medical Center of Chinese PLA General Hospital from January 2014 to July 2022. Patients with CKD who had one or more 24-hour urinary electrolyte excretion tests at intervals of more than three months were included in the subgroup analysis.

Exclusion criteria

* Patients with hemodialysis therapy and urine volume less than 500ml were excluded.

Design outcomes

Primary

Measure	Time frame	Description
Kidney disease progression	2014.1.1-2022.7.31	eGFR decline \> 50%; dialysis; kidney transplant
Death	2014.1.1-2022.7.31	All cause death

Secondary

Measure	Time frame	Description
Cardiovascular disease	2014.1.1-2022.7.31	myocardial infarction, angina pectoris, stable heart failure, peripheral artery disease , revascularization, cerebrovascular events

Outcome results