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A New Deep-learning Based Artificial Intelligence Iterative Reconstruction (AIIR) Algorithm in Low-dose Liver CT

Evaluation of a New Deep-learning Based Artificial Intelligence Iterative Reconstruction (AIIR) Algorithm in Different Enhancement Phases of Low-dose Liver CT

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05550012
Enrollment
100
Registered
2022-09-22
Start date
2022-09-30
Completion date
2023-04-30
Last updated
2022-09-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Deep Learning

Brief summary

CT-enhanced scans are routine imaging modality for the diagnosis and follow-up of liver disease. However, this means that patients will receive more radiation dose. Therefore, it is necessary to reduce the radiation dose received by patients as much as possible. Deep learning-based reconstruction algorithms have been introduced to improve image quality recently. For many years, researchers attempt to maintain image quality using an advanced method while reducing radiation dose. Recently, a new deep-learning based iterative reconstruction algorithm, namely artificial intelligence iterative reconstruction (AIIR, United Imaging Healthcare, Shanghai, China) has been introduced. In this study, we evaluate the image and diagnostic qualities of AIIR for low-dose portal vein and delayed phase liver CT with those of a KARL method normally used in standard-dose CT.

Detailed description

In our hospital, patients with abdominal pelvic cancer undergo follow-up low-dose CT for the evaluation of treatment plan after clinical treatment or disease progress. The raw-data of low-dose CT were collected retrospectively and reconstructed using KARL and AIIR algorithm. In this study, we evaluate the image and diagnostic qualities of AIIR for low-dose portal vein and delayed phase liver CT with those of a KARL method normally used in standard-dose CT.

Interventions

those patients undergo low-dose liver CT in portal vein and delayed phase.

Sponsors

Qianfoshan Hospital
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
NONE

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

* those scheduled for contrast-enhanced liver CT

Exclusion criteria

* images affected by artifacts (motion or implants)

Design outcomes

Primary

MeasureTime frameDescription
signal-to-noise ratio (SNR)6 monthsEvaluate the image qualities of AIIR for low-dose portal vein and delayed phase liver CT with those of a KARL method normally used in standard-dose CT
contrast to noise ratio (CNR)6 monthsEvaluate the image qualities of AIIR for low-dose portal vein and delayed phase liver CT with those of a KARL method normally used in standard-dose CT
diagnostic confidence6 monthsEvaluate the diagnostic qualities of AIIR for low-dose portal vein and delayed phase liver CT with those of a KARL method normally used in standard-dose CT

Countries

China

Contacts

Primary ContactQingshi Zeng
zengqs2021@163.com18560081565

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026