Discriminant Ability of the Shock Index, Modified Shock Index, and Reverse Shock Index Multiplied by the Glasgow Coma Scale on Mortality in Adult Trauma Patients: A PATOS Study

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05549986

Enrollment

105641

Registered

2022-09-22

Start date

2016-01-01

Completion date

2020-12-31

Last updated

2022-09-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Morality, Shock, Traumatic, Trauma

Keywords

Shock index(SI), Modified Shock Index (MSI), Reverse Shock Index Multiplied by the Glasgow Coma Scale (rSIG), Mortality, Pan-Asian Trauma Outcomes Study (PATOS)

Brief summary

We evaluated a cohort of adult trauma patients transported to emergency departments. The first vital signs were used to calculate the SI, MSI, and rSIG. The areas under the receiver operating characteristic curves (AUROCs) and test results were used to compare the discriminant performance of the indices on short-term mortality and poor functional outcome. A subgroup analysis of geriatric patients, traumatic brain injury, penetrating injury, and non-penetrating injury was performed.

Interventions

OTHERObservational

Observational

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* Adult patients (≥18 years) EMS-transported from January 2016 to December 2020

Exclusion criteria

* Patients with missing entries of age, sex, triage, SBP, DBP, HR, or GCS were excluded. * Entries with missing records of in-hospital mortality or 30-day mortality were excluded from the short-term mortality cohort analyses. * Patients without a Modified Rankin Scale (MRS) record at discharge were excluded from the functional outcome cohort analyses.

Design outcomes

Primary

Measure	Time frame	Description
Discriminant power of SI, MSI, and rSIG on short-term mortality for adult traumatic patients	30 days	AUROC in associated with short-term mortality with SI, MSI, rSIG

Secondary

Measure	Time frame	Description
Discriminant power of SI, MSI, and rSIG on functional outcome for adult traumatic patients	We defined no symptoms, no significant disability, slight disability, and moderate disability (MRS 0-3) as favorable functional outcomes and moderately severe disability, severe disability, and death (MRS 4-6) as poor functional outcomes	AUROC in associated with functional outcome with SI, MSI, rSIG

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026