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ANGH Prospective Cohort of Mild and Severe Acute Biliary Pancreatitis

ANGH Prospective Cohort of Mild and Severe Acute Biliary Pancreatitis

Status
Terminated
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05549349
Acronym
CAPABLES
Enrollment
2000
Registered
2022-09-22
Start date
2022-10-10
Completion date
2024-07-10
Last updated
2025-03-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Biliary Pancreatitis

Brief summary

The main objective of this work is to evaluate the recurrence of biliary episodes before cholecystectomy (hepatic colic, lithiasic migration, cholangitis, cholecystitis, pancreatitis, necrosis infections) in patients with acute biliary pancreatitis of any severity depending on the type of nutrition (oral, enteral or parenteral).

Detailed description

Acute pancreatitis (AP) is one of the frequent causes of hospitalization in gastroenterology with an annual incidence of 13-45 cases per 100,000 patients. If we refer to the data in the white paper, hospitalizations for abdominal emergencies, such as PA, take place in at least 60% of cases in General Hospital Centers (CHG). Among these AP, approximately 40% of AP are secondary to a biliary lithiasis pathology. The main modalities of the initial management of AP have been the subject of several national and international recommendations and consensuses. Although it is well accepted that early refeeding during the first 48 hours reduces the appearance of a systemic inflammatory response syndrome (SIRS) or a collection infection, the feeding methods in the event of pancreatitis Acute biliary (ABP) during the acute phase using the oral route if it is tolerated or the enteral route by nasogastric tube before cholecystectomy remains debated. Thus, in case of delayed cholecystectomy after AP, there is no consensus on the feeding methods after the acute phase (oral or enteral) until cholecystectomy nor on the benefit of a prophylactic endoscopic sphincterotomy in the absence of cholangitis.

Interventions

PROCEDURECholecystectomy

Gallbladder removal

Sponsors

Julia TRAVAGLI
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Adult over 18 years old * Affiliated to a social security scheme. * Patients with acute biliary pancreatitis

Exclusion criteria

* Patients with chronic pancreatitis * Patients with a previous cholecystectomy * Patients under guardianship, curatorship or legal protection

Design outcomes

Primary

MeasureTime frameDescription
biliary events3 monthAssess the recurrence of biliary events before cholecystectomy

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026