Continuous EMG Measurements in Children With Asthma During Sleep

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05547477

Enrollment

Registered

2022-09-21

Start date

2022-09-30

Completion date

2023-01-31

Last updated

2022-09-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Asthma in Children, Electromyography, Sleep-Disordered Breathing

Brief summary

The objective of this study is to investigate whether electromyography of the diaphragm during sleep in asthmatic children can be used to objectively monitor asthma control.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

4 Years to 18 Years

Healthy volunteers

Inclusion criteria

* Paediatrician diagnosed asthma or bronchial hyperresponsiveness * Aged 4 till 18 * Admitted to the paediatric ward of Medisch Spectrum Twente

Exclusion criteria

* Admittance to the ICU * Patient has ICD or pacemaker * Parents and/or patient cannot understand or speak Dutch * Does not fit in one of the available Hexoskin shirts

Design outcomes

Primary

Measure	Time frame	Description
Breathing registration in sleep using electromyography	From admittance to the ward, up to 12 hours	Amplitude of the EMG signal will be used to obtain breathing waveforms.

Secondary

Measure	Time frame	Description
Prediction of asthma exacerbations	After inclusion of all subjects, up to 3 months	A machine learning model will be applied to be able to predict an asthma exacerbation before it occurs

Contacts

Primary ContactRuben Smink

R.K.Smink@mst.nl+31 53 487 2310

Backup ContactPascal Keijzer

P.Keijzer@mst.nl+31 53 487 2310

Outcome results