Neoplasms Pancreatic
Conditions
Keywords
pancreatic ductal adenocarcinoma, prognostic model, tumor-infiltrating immune cell, staging
Brief summary
The AJCC TNM staging system is the prevailing method in prognostic evaluation of pancreatic ductal adenocarcinoma (PDAC) at present , but it did not include factors such as the tumor immune microenvironment that are known to exert a profound impact on patients'clinical outcome. This study was aimed to develop a comprehensive and effective prognostic score model to predict prognosis and guide clinical management for postoperative PDAC patients.
Interventions
PROCEDUREpancreatic cancer surgery
Surgical resection of pancreatic cancer，including radical or palliative surgery
Sponsors
Zhejiang University
Study design
Observational model
CASE_ONLY
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
1. Pathologically confirmed PDAC 2. Achievement of surgical resection (including radical or palliative surgery)
Exclusion criteria
1. Lost to follow-up 2. Simultaneous presence of other tumors 3. Died in three months after surgery
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| overall survival | after pancreatic cancer surgery until october 31, 2020 | the number of months from the date of surgery to the date of the last follow-up visit or time of death. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| disease-free survival disease-free survival disease-free survival disease-free survival | after pancreatic cancer surgery until october 31, 2020 | the number of months from the date of surgery to the date of first confirmable recurrence or death |
Countries
China
Outcome results
None listed