Sarcopenia, Frailty
Conditions
Brief summary
Hand grip strength has been shown to be a predictor of adverse cardiovascular outcomes in the elderly population. This study aims to investigate whether measurement of hand grip strength could be used as a predictor of prolonged hospital stay after cardiac surgery in elderly patients.
Interventions
Preoperative hand grip strength will be measured in kilograms using a digital hand dynamometer (Baseline Smedley Digital Hand Dynamometer, Model 12-0286, Baseline Evaluation Instruments, China). Participants will be instructed to grip the hand dynamometer for 5 seconds with their dominant hand 3 times. They will be allowed to rest for 20 second between each grip. The highest measurement of 3 attempts will be recorded. Participants will be categorized as strong grippers or weak grippers according to Fried criteria as previously defined by Linda P. Fried and colleagues. A weak grip will be defined as follows: For men: BMI ≤24: hand grip strength ≤29 kg; BMI =24.1 to 28: hand grip strength ≤30 kg; BMI \>28: hand grip strength ≤32 kg For women: BMI ≤23: hand grip strength ≤17 kg; BMI =23.1 to 26: hand grip strength ≤17.3 kg; BMI =26.1 to 29: hand grip strength ≤18 kg; BMI \>29: hand grip strength ≤21 kg
Sponsors
Study design
Eligibility
Inclusion criteria
* Age ≥70 years * Undergoing isolated coronary artery bypass grafting or isolated valve surgery or combined coronary and valve procedures * Being oriented and cooperative enough to understand and comply with the instruction of gripping the hand dynamometer
Exclusion criteria
* Age \<70 years * Emergent status * Hemodynamic instability * Inability to cooperate due to neurocognitive disorder * Loss of upper extremity motor function of any degree (such as due to previous stroke) * History of upper extremity amputation of any level
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Prolonged hospital stay | 14 days | Prolonged hospital stay is defined as postoperative hospital stay for ≥14 days. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Prolonged intensive care unit stay | 48 hours | Prolonged intensive care unit stay is defined as postoperative intensive care unit stay for \>48 hours. This includes sum of all time spent in intensive care unit including unplanned returns. |
| Prolonged mechanical ventilation | 12 hours | Prolonged mechanical ventilation is defined as mechanical ventilation of \>12 hours. This includes re-intubations and non-invasive mechanical ventilation. |
Countries
Turkey (Türkiye)