Skip to content

The Validation and Development of Termination-of-Resuscitation (TOR) Rules in OHCA Patients in Asia Countries

The Validation and Development of Termination-of-Resuscitation (TOR) Rules in Patients Following Out-of-Hospital Cardiac Arrest (OHCA) in Asia Countries

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05545176
Enrollment
140000
Registered
2022-09-19
Start date
2007-01-01
Completion date
2032-12-31
Last updated
2026-02-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Out-Of-Hospital Cardiac Arrest

Keywords

Out-Of-Hospital Cardiac Arrest, OHCA

Brief summary

Objectives/Hypotheses 1. Prehospital termination-of-resuscitation (TOR) rules were developed in North American and European sites. Whether they remained valid in different geographic, ethnic, and cultural background areas is still under debate. 2. Differences in characteristics of out-of-hospital cardiac arrests (OHCAs) and configurations of emergency medical service (EMS) between the Western and Asian countries, including relatively lower rate of presenting shockable rhythm (i.e. ventricular fibrillation / ventricular tachycardia; VF/VT), lower rates of bystander CPR, less advanced life support (ALS) implementation, and less public access defibrillators, might create potential threats to the prediction accuracy of TOR rules. 3. We aim to conduct a study to validate the performance of ever published TOR rules in Asian OHCA population, including non-traumatic, traumatic, and pediatric OHCA patients. Furthermore, assess the possible variables that may impact the performance of TOR rules. 4. We also aim to develop new TOR rules based on PAROS registry for Asia population, focusing on non-traumatic, traumatic, and pediatric OHCA patients, respectively.

Interventions

OTHERtermination of resuscitation rules

Use retrospective data to analyze the accuracy termination of resuscitation rules and further develope a termination of resuscitation rule.

Sponsors

National Taiwan University Hospital
Lead SponsorOTHER
Singapore Clinical Research Institute
CollaboratorOTHER

Study design

Observational model
OTHER
Time perspective
OTHER

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum

Inclusion criteria

* out of hospital cardiac arrest (OHCA) patients

Exclusion criteria

* age \<18 years * non-EMS transport to the emergency department * obvious signs of death (e.g. decapitation, rigor mortis, lividity, and decapitation) or having do-not-resuscitate (DNR) orders * missing data despite meeting the inclusion criteria.

Design outcomes

Primary

MeasureTime frameDescription
survival to hospital dischargesurvival to 30-day hospitalisationsurvival to 30-day hospitalisation

Secondary

MeasureTime frameDescription
Cerebral Performance Categories Scale (CPC)CPC within 30-day hospitalisationCPC Scale 1\~5, minimum value: 1; maximum value:5; lower score means greater outcome

Countries

Taiwan

Contacts

CONTACTShu-Hsien Hsu, MPH
pedroe929@gmail.com
PRINCIPAL_INVESTIGATORShu-Hsien Hsu, MPH

National Taiwan University

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 27, 2026