Predictive Model for Pain After TACE

A Predictive Model for Pain After Transarterial Chemoembolization

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05545046

Enrollment

228

Registered

2022-09-19

Start date

2019-09-01

Completion date

2021-01-31

Last updated

2022-09-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hepatocellular Carcinoma

Brief summary

The main aim of this study was to analyze the risk factors that helped to predict the pain after transarterial chemoembolization (TACE).This was a prospective observational study enrolled all hepatocellular carcinoma (HCC) patients undergoing TACE in our hospital. Pain score at rest was assessed after TACE by the patients themselves using a Visual Analogue Scale (VAS). Independent variables such as age, gender, tumor location, tumor size and number, drug delivery method and presence of portal vein tumor thrombosis (PVTT) were recorded and analyzed.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

34 Years to 87 Years

Inclusion criteria

* A diagnosis of HCC was confirmed either histologically or based on consistent findings obtained from at least two imaging techniques.

Exclusion criteria

* patients aged \< 18 year * significant heart or lung dysfunction * use of additional analgesics to relieve pain during TACE * cognitive impairment * use of psychiatric medications * drug or alcohol abuse

Design outcomes

Primary

Measure	Time frame	Description
Visual Analogue Scale (VAS)	0 hour after TACE by the patients themselves using a Visual Analogue Scale (VAS)	After local anesthesia with an injection of 10 mL of 2% lidocaine, all the patients enrolled in this study received percutaneous femoral artery puncture. An arterial catheter was inserted into the femoral artery and subsequently placed in the hepatic artery. Then, a conventional TACE or a DEB-TACE procedure was performed. After TACE, all patients received supportive treatment including antiemetics, liver protection, non-steroidal anti-inflammatory drugs.

Countries

China

Outcome results