A Study of Paravertebral Block in Thoracic Outlet Syndrome

Pre-Operative and Post-Operative Paravertebral Block on Patients With Thoracic Outlet Syndrome.

Status

Enrolling by invitation

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT05544721

Enrollment

Registered

2022-09-16

Start date

2022-10-05

Completion date

2027-08-31

Last updated

2025-11-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thoracic Outlet Syndrome

Keywords

First rib resection procedure

Brief summary

This research is being done to evaluate the effects of receiving only a paravertebral block prior to first rib resection procedure versus receiving the block both pre and post procedure.

Interventions

DRUGRopivacaine

0.5% 3-4 mL per level, with levels T1 and T2 will be used as the block injectate

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

SUPPORTIVE_CARE

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

\- All Thoracic Outlet Syndrome patients scheduled for first rib resection surgery.

Exclusion criteria

* Patients who are pregnant. * Patients with prior first rib resection on side of presentation. * Patients with complex regional pain syndrome (CRPS). * Patients with brachial plexus disorder. * Patients with cervical rib.

Design outcomes

Primary

Measure	Time frame	Description
Change in pain level	Time of discharge (approximately 1 day), day 1 post-op, day 3 post-op, day 7 post-op, and day 14 post-op	Measured using the pain visual analog scale (VAS). The VAS line will be 100 mm long with each end marked with no pain on the left, and worst possible pain on the right; participant identify their pain level by indicating a point on the line between each end and this point is measured from the No pain end, and the number of millimeters is reported as the pain score.

Secondary

Measure	Time frame	Description
Change in quality of life	Time of discharge (approximately 1 day), day 1 post-op, day 3 post-op, day 7 post-op, and day 14 post-op	Measured using the Short Form (SF-36) Health Survey; The SF-36 Health Survey is a 36-item, participant-reported survey that measures patient health and disability. Possible scores range from 0 to 100, with 0 indicating maximum disability, and 100 indicating no disability
Length of stay	Approximately 1 day	Number of hours subjects are in the hospital following their surgical procedure

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026