Database of Monochorionic Pregnancies

Standardized Prenatal Management and Perinatal Outcome of Complicated Monochorionic Pregnancies

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05543499

Enrollment

1200

Registered

2022-09-16

Start date

2022-10-01

Completion date

2027-12-01

Last updated

2026-05-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Monochorial Monoamniotic Placenta, Monochorionic Diamniotic Placenta, Twin; Complicating Pregnancy, Twin Reversal Arterial Perfusion Syndrome, Twin to Twin Transfusion Syndrome

Keywords

multiple pregnancies, Twins

Brief summary

The purpose of this study is to collect and analyze data regarding natural history, indications for fetal interventions, and maternal and fetal/neonatal outcomes associated with complicated monochorionic twin pregnancy.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* The study population will consist of MC pregnancies (maternal, fetal, and neonatal data) that have undergone evaluation and/or treatment for complications attributable to monochorionic twin pregnancy at the University of Miami. * Maternal age 18 years and older.

Exclusion criteria

* Participation declined or consent not granted in prospective arm * Loss to follow-up

Design outcomes

Primary

Measure	Time frame	Description
Number of participants with Preterm Delivery	Up to 42 weeks gestation	Preterm delivery is defined as birth \<37 weeks gestation
Number of participant with Premature Spontaneous Rupture of the Membranes	Up to 42 weeks	As per clinical evaluation
Number of Infant Deaths	Up to 12 months post infant delivery	The Number of Infant Deaths

Countries

United States

Contacts

PRINCIPAL_INVESTIGATORRodrigo Ruano, MD PhD

University of Miami

Outcome results