Endometrial Cancer
Conditions
Brief summary
Objective: Calculate the incidence of P53 immunohistochemistry abnormal staining in endometrial cancer and to identify its relation with disease stages, pathological types and grading. Patients and methods: 100 cases of endometrial cancer will be included in the study, recruited from Alexandria university hospital gyne-oncology unit. Surgical staging, histopathological examination and immunohistochemistry of p53 were done to all cases to calculate the incidence of P53 immunohistochemistry abnormal staining in endometrial cancer and to identify its relation with disease stages, pathological types, grading. Keywords: P53 immunohistochemistry, endometrial cancer, clinicopathological relation.
Interventions
OTHERp 53 immunohistochemistry positive staining and relation to stages ,pathological types and grading
p 53 immunohistochemistry positive staining and relation to stages ,pathological types and grading
Sponsors
Hossam Hassan Aly Hassan El Sokkary
Study design
Observational model
CASE_ONLY
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
FEMALE
Inclusion criteria
* endometrial cancer patients
Exclusion criteria
* patients unfit for surgery
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| p53 immunohistochemistry | 1 month | Incidence of abnormal staining of p53 in endometrial cancer |
| Relation of p53 abnormal staining with disease stages | 1month | Relation of p53 abnormal staining with disease stages |
| Relation of p53 abnormal staining with disease pathological types | 1 month | Relation of p53 abnormal staining with disease pathological types |
| Relation of p53 abnormal staining with disease pathological grades | 1 month | Relation of p53 abnormal staining with disease pathological grades |
Countries
Egypt
Outcome results
None listed