Metabolic Syndrome, Overweight
Conditions
Brief summary
This randomized, double-blind, placebo-controlled, and parallel clinical study aims to investigate the effectivness of a pumpkin seed extract (IRK-19®) on weight management.
Interventions
DIETARY_SUPPLEMENTPumpkin seed extract (IRK-19)
Placebo: Dietary fiber powder, two capsules/day (600 mg/day), continued use for 3 months Treatment: Pumpkin seed extract powder, two capsules/day (600 mg/day), continued use for 3 months
Sponsors
Taipei Medical University WanFang Hospital
Greenyn Biotechnology Co., Ltd.
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
20 Years to 60 Years
Healthy volunteers
Yes
Inclusion criteria
1. BMI: 25-30 kg/m2 2. Waistline circumference: ˃ 80 cm
Exclusion criteria
1. Pregnant women or preparing for pregnancy. 2. Lactating women. 3. Women gave birth 6 months before the study. 4. Subject uses diuretic, corticosteroids, anti-depressant medications, or antipsychotic medications. 5. Subject has undertaken obesity-related surgeries within one year prior to the study or other surgeries within six months prior to the study. 6. Change of body weight of subject is over 5% within 3 months before the study. 7. Subject has serious diseases (e.g., cardiovascular diseases). 8. Cancer patient. 9. Subject has engaged in another study within 3 months before the study. 10. Subject uses another dietary supplement related to weight management during the study.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Biochemistry | Week 0 | Total cholesterol |
| Anthropometric measurement | Week 0 | Body weight |
| Body composition analysis | Week 0 | Body fat |
Countries
Taiwan
Outcome results
None listed