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Long-term Outcome Following Concomitant Surgical Ablation for Atrial Fibrillation at University Hospital Basel: A Retrospective Study

Long-term Outcome Following Concomitant Surgical Ablation for Atrial Fibrillation at University Hospital Basel: A Retrospective Study

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05542017
Enrollment
123
Registered
2022-09-15
Start date
2018-02-26
Completion date
2019-10-10
Last updated
2022-09-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atrial Fibrillation, Maze Procedure

Keywords

Surgical Ablation, Cardiac Surgery

Brief summary

This retrospective single-centre study aims to examine the success rate of concomitant surgical ablation in patients with atrial fibrillation (AF) with an up to eight years follow-up period. Moreover, the focus of this study was to identify variables which predict freedom from AF, such as the type of AF, lesion set performed, energy source used and the patient's characteristics.

Interventions

PROCEDURESurgical Ablation for Atrial Fibrillation

Surgical ablation in combination with other cardiac procedures through a median sternotomy or thoracotomy. Main procedures were valve surgery (i.e. repair, replacement) and/or coronary artery bypass grafting (CABG). Surgical ablation procedures for atrial fibrillation were divided into three different groups according to Heart Rhythm Society (HRS) expert consensus 2017: (1) Pulmonary vein isolation alone; (2) Pulmonary vein isolation combined with left atrial lesion sets; (3) and biatrial procedure.

Sponsors

University Hospital, Basel, Switzerland
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

* concomitant surgical ablation for atrial fibrillation * performed between January 2011 and January 2017 at University Hospital Basel

Exclusion criteria

* stand-alone procedure * surgical ablation for atrial flutter

Design outcomes

Primary

MeasureTime frameDescription
Freedom from AF one year after surgical ablation12 monthsone-year success

Secondary

MeasureTime frameDescription
Need of additional arrhythmia interventionsfrom surgical ablation until 10th October 2019repeat ablation procedures, electrical cardioversion, pacemaker implantation or implantable cardioverter-defibrillator (ICD) implantation
Use of oral anticoagulationfrom surgical ablation until 10th October 2019
Freedom from atrial fibrillation (AF) and atrial flutter (AFL) after removal from antiarrhythmic drug therapyfrom surgical ablation until 10th October 2019
Mortalityfrom surgical ablation until 10th October 2019
Evolution of left atrial sizefrom surgical ablation until 10th October 2019
Perioperative morbidityfrom surgical ablation until 10th October 2019

Countries

Switzerland

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026