Mechanical Ventilation Complication
Conditions
Brief summary
Three drops of peppermint oil will be dropped on a cotton ball that will be fixed in the patient's collar. In the placebo group, peppermint oil will be replaced with water.
Detailed description
Mechanical ventilathetion increases the anxiety of critically ill patients. The physiological parameters of those patients are affected by stress. Peppermint inhalation reduces stress and improves physiological parameters in many studies, but none of these studies used peppermint inhalation on mechanically ventilated patients. Patients who are conscious on mechanical ventilation via endotracheal via tube will be randomly assigned to two groups. Patients will be kept intubated and mechanically ventilated. Nothing will be changed in patients' mechanical ventilation data. The intervention group will receive peppermint inhalation intervention, and the placebo group received water inhalation intervention. Patients in both groups will be assessed for their smell ability by Sniffin Sticks-test before starting the interventions. Three drops of undiluted peppermint oil will be dropped on a cotton ball. Then it will be placed about 20 cm from the patient's nose. It will be fixed on the patient's collar. In the placebo group, the cotton ball will be soaked in water. Then, patients will be monitored for one hour.
Interventions
OTHERAromatherapy
Peppermint aroma inhalation
OTHERPlacebo
Water inhalation
Sponsors
Alexandria University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
TRIPLE (Subject, Caregiver, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
Patients with * (1) endotracheal tube (ETT) * (2) mechanical ventilation with spontaneous breathing modes which are CPAP, PIPAP and PSV * (3) FOUR score equal to or more than 13, * (4) RASS score from -1 to +4.
Exclusion criteria
Patients with * (1) respiratory asthma * (2) chronic obstructive pulmonary disease * (3) acute respiratory distress syndrome, * Sniffin' Sticks-test score of smell less than 17
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Heart rate | Change from baseline heart rate at one hour. | The number of heart beats in one minute. It will be reported in beat per minute. |
| Respiratory rate | Change from baseline respiratory rate at one hour. | The number of breaths in one minute. It will be reported in breath per minute. |
| Mean blood pressure | Change from baseline mean blood pressure at one hour. | Mean blood pressure equal diastolic blood pressure + 1/3 \[systolic blood pressure - diastolic blood pressure\]. It will be reported in millimeters of mercury (mmHg). |
| Pain score | Change from baseline pain score at one hour. | It will be measured using non verbal pain assessment scale. It consists of five categories; face, movement, guarding, physiology, and respiratory items. It will be reported in score. The maximum score of the scale is 10 which means extremely sever pain, and the minimum score is zero which means no pain. |
Countries
Egypt
Outcome results
None listed