Periodontal Diseases
Conditions
Brief summary
The adjunctive topical subgingival application ozone gel creates a great improvements in the clinical, bacteriological and immunological parameters over the gold standard of periodontal pocket treatment alone.
Detailed description
The aim of this study is to compare the effect of using ozone gel as a locally delivered adjunct to scaling and root planning versus scaling and root planning alone on the clinical parameters in stageIII grade B in periodontitis patients with controlled diabetic patients.
Interventions
DRUGOzone gel
application of Ozone gel after scaling by ultrasonic scaler in the bottom of periodontal pocket
Sponsors
Cairo University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
1. Patient with controlled diabetic type II. (HgA1C \<7) (Mori et al., 2021) 2. Adult patients above 18 years old. 3. Patients with stage III and grade B periodontitis. 4. Patients accept 3-months follow-up period (cooperative patients). 5. Patients provide an informed consent
Exclusion criteria
* 1\. Presence of prosthetic crowns. 2. Extensive restorations. 3. Periodontal therapy within the last 12 months. 4. Having surgical therapy or undergoing orthodontic treatment. 5. Ongoing drug therapy that might have an impact on the clinical signs and symptoms of periodontitis. 6\. The use of antibiotics or anti-inflammatory drugs 1 month prior to the procedure and till the end of 3 months of follow-up. 7\. Smokers. 8. Pregnant females. 9. Any known allergies
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Clinical Attachment Level | 3months | clinical attachment gain by using UNC15 Periodontal probe/ numerical data |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Probing Depth | 3 months | measuring probing depth by using UNC15 Periodontal probe/numerical data |
| plaque index | 3 months | measuring it visually/numerical data |
| Dentinal Hypersensitivity | 7 days | measuring it using VAS scale |
| Bleeding on Probing visually/numerical data | 3 months | measuring it visually/numerical data |
Countries
Egypt
Contacts
Primary ContactAbeer A Barahim, BDS
Backup ContactNesma M Shemais, PhD
Outcome results
None listed