Mental Health Issue, Postpartum, Pregnancy
Conditions
Keywords
Pregnancy, Postpartum, Mental Health
Brief summary
The overall goal of the BUMPP study is to improve our understanding of a range of moods, feelings, and thoughts that women can experience during pregnancy and soon after they give birth. This study will examine how these moods, feelings, and thoughts are related to changes in hormonal and immune health that women experience during and after pregnancy, and to mother-baby relationships and infant development in the early postpartum months.
Interventions
OTHERObservation Group
No intervention; this is an observational study.
Sponsors
University of Minnesota
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to No maximum
Inclusion criteria
* 18 years or older * 35 weeks pregnant or less * carrying only one baby (not twins or triplets) * first time giving birth * can speak/read/write in English
Exclusion criteria
* major medical health condition like a heart, kidney, or liver disease or HIV * currently taking corticosteroids, progesterone, or immunosuppressive medications that might impact the samples we are taking in this research study * have regularly used alcohol, tobacco, or recreational drugs (such as marijuana or prescription drugs for non-medical reasons) during pregnancy (regularly means more than a few times total, such as on a monthly, weekly, or daily basis)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Bayley Scales of Infant Development, 4th edition, to assess infant cognitive development | 2 months postpartum | Assessed at in-person laboratory session (session 4) |
| Self-report questionnaire measure of symptoms of psychosis (subscales of Symptom Checklist-90) | 35 weeks of pregnancy through 2 months postpartum | Assessed at each of 4 sessions |
| Mother-infant behavior during 5 min play episode coded using Global Rating Scales | 2 months postpartum | Assessed at in-person laboratory session (session 4) |
| Self-report questionnaire measure of anxiety symptoms (Generalized Anxiety Disorder-7) | 35 weeks of pregnancy through 2 months postpartum | Assessed at each of 4 sessions |
| Self-report questionnaire measure of manic symptoms (Highs Scale) | 35 weeks of pregnancy through 2 months postpartum | Assessed at each of 4 sessions |
| Self-report questionnaire measure of depressive symptoms (Edinburgh Postnatal Depression Scale) | 35 weeks of pregnancy through 2 months postpartum | Assessed at each of 4 sessions |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Monthly cortisol levels determined from hair sample | 35 weeks of pregnancy through 2 months postpartum | 1 sample at session 4 |
| Cytokine levels determined from finger prick blood spot | 35 weeks of pregnancy through 2 months postpartum | 3 samples (sessions 1, 2, and 4) |
Countries
United States
Outcome results
None listed