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Validation of the Chinese Version of Oxford Depression Questionnaire

Psychometric Properties of the Oxford Depression Questionnaire in Chinese Patients With Mood Disorders

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05535270
Enrollment
272
Registered
2022-09-10
Start date
2022-01-01
Completion date
2023-06-30
Last updated
2023-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Emotional Blunting, Mood Disorders

Brief summary

Mood disorders are a group of psychiatric disorders that can affect a person's mood, energy, and motivation. Emotional blunting has been observed in clinical practice in patients with mood disorders. Emotional blunting has a negative impact on patients' overall treatment and leads to poorer adherence. The Oxford Depression Questionnaire (ODQ) is a measuring instrument of emotional blunting. The ODQ is expected to be a scientifically valid tool for detecting emotional blunting. The ODQ has high construct validity and internal reliability. However, no scientific validity studies have been conducted on ODQ in Chinese population. Therefore, this study is intended to investigate the reliability and validity of the ODQ in Chinese patients with mood disorders.

Interventions

DIAGNOSTIC_TESTOxford Depression Questionnaire (ODQ)

The Oxford Depression Questionnaire (ODQ)is a patient-centered questionnaire. The scale contains three sections: i) the patient's experience in the past week; ii) the patient's experience before the illness worsened, and iii) the patient's emotional feelings about receiving antidepressant treatment. The 26-item questionnaire contains four dimensions of emotional blunting: not caring (NC), emotional detachment from others (ED), reduction in positive emotions (RP), and general reduction in emotions (GR). Patients not taking antidepressants were only required to rate the first two sections .

Sponsors

First Affiliated Hospital of Zhejiang University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
13 Years to 65 Years
Healthy volunteers
Yes

Inclusion criteria

1\) both biological parents were Han Chinese; 2) currently diagnosed with major depressive disorder or bipolar disorder according to the Mini International Neuropsychiatric Interview for Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition; 3) aged 13-65 years; 4) can complete the self-assessment questionnaires.

Exclusion criteria

1\) currently diagnosed with neurological diseases or other major psychiatric disorders, e.g., schizophrenia, cognitive impairment, substance abuse; 2) diagnosed with severe somatic illnesses, such as diabetes and cardiovascular diseases;

Design outcomes

Primary

MeasureTime frameDescription
Oxford Depression Questionnaire (ODQ)baselineTo analyze reliability and validity of the ODQ.

Secondary

MeasureTime frameDescription
Beck Depression Inventory-II (BDI-II)baselineTo analyze criterion validity of the Chinese version of the ODQ
Montgomery-Asberg Depression Rating Scale (MADRS)baselineTo analyze correlation with ODQ
Oxford Depression Questionnaire (ODQ)2 weeks after baselineTo analyze Test-retest reliability coefficients of the ODQ.

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026