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Risk Factors for Post ACL Reconstruction Pain

Risk Factors for Postoperative Pain After Arthroscopic Anterior Cruciate Ligament Reconstruction

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05533489
Enrollment
924
Registered
2022-09-09
Start date
2022-10-01
Completion date
2024-12-31
Last updated
2022-09-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Risk Factors for Post ACL Reconstruction Pain

Brief summary

In 2006, approximately 130,000 arthroscopic anterior cruciate ligament reconstructions were performed in the United States, and the number is increasing each year. Despite being a minimally invasive procedure, pain is the most common postoperative problem after arthroscopic anterior cruciate ligament reconstruction associated with cost, postoperative opioid consumption, opioid-related side effects, quality of life, patient satisfaction, and delayed discharge. Over two-thirds of the patient receiving arthroscopic anterior cruciate ligament surgery have moderate to severe pain.

Detailed description

At present, multimodal analgesia is a successful mainstay treatment for arthroscopic anterior cruciate ligament surgery which range from opioid, paracetamol, non-steroidal anti-inflammatory agents (NSAIDs), local anesthetic agents, ketamine, corticosteroid, and cold compression therapy. Previous study showed femoral nerve block reduces pain score but also increases incidence of falling. Afterward, a study on adductor canal block showed equivalent postoperative analgesia while preserving quadriceps strength. Furthermore, a few studies were conducted to determine risk factors for postoperative pain after arthroscopic anterior cruciate ligament surgery, but results are contradictory. Previous research found risk factors for postoperative pain after arthroscopic anterior cruciate ligament surgery are female, young age, smoker, preoperative visual analog scale score ≥3, tourniquet time \> 50 minutes, and cartilage injury. In addition, evidence showed higher preoperative visual analog scale, and previous opioid use are associated with greater amount of opioid consumption. In contrary, some evidence showed no effect of age, sex, body mass index (BMI), tourniquet time, type of anesthesia on post postoperative pain after arthroscopic anterior cruciate ligament surgery.

Interventions

OTHERNo intervention

No intervention This study is a retrospective descriptive study.

Sponsors

Prince of Songkla University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

Patients undergoing primary unilateral arthroscopic anterior cruciate ligament reconstruction with or without unilateral cartilage/meniscus injury with or without other ligaments injury (posterior cruciate ligament/medial collateral ligament/lateral collateral ligament) Age ≥ 15 years

Design outcomes

Primary

MeasureTime frameDescription
To find risk factors for moderate to severe postoperative pain after arthroscopic anterior cruciate ligament reconstruction in the first 72 hours.Three daysTo find risk factors for moderate to severe postoperative pain after arthroscopic anterior cruciate ligament reconstruction in the first 72 hours

Secondary

MeasureTime frameDescription
To find incidence of moderate to severe pain after arthroscopic anterior cruciate ligament reconstruction in the first 72 hoursThree daysTo find incidence of moderate to severe pain after arthroscopic anterior cruciate ligament reconstruction in the first 72 hours
To find analgesic requirement after arthroscopic anterior cruciate ligament reconstruction for 1 yearOne year after dischargeTo find analgesic requirement after arthroscopic anterior cruciate ligament reconstruction for 1 year

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026