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Serum Prostatic Specific Antigen Changes After Bipolar and Monopolar TURP

Serum Prostatic Specific Antigen (PSA) Changes After Bipolar and Monopolar Transurethral Resection of the Benign Prostatic Hyperplasia, a Randomized Controlled Study.

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05533047
Enrollment
2
Registered
2022-09-08
Start date
2022-10-01
Completion date
2023-11-01
Last updated
2022-09-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

PSA Changes After TURP

Brief summary

To use PSA levels after bipolar and monopolar transurethral resection of the benign prostatic hyperplasia as an indicator of the quality of resection .

Detailed description

PSA is a protein produced from the prostate epithelium and secreted in semen in huge amounts , small amount find its way to the circulation ,its function is to allow mobility of the sperms by interacting with the Semenogelin . clinical BPH can be defined as prostate adenoma/adenomata, causing a varying degree of BOO, which may eventually cause harm to the patients ,Treatment of this condition varies from conservative, medical and surgical depending on factors related to the patient and the surgeon preference . The early reports of minimally invasive treatment of the prostate dated back to 1937, since then and remarkable development is noticed . TURP is the golden treatment in the BPH . Studies compare between the methods according the blood transfusion , operation time retention after catheter removal , urethral complications , TUR syndrome and hospital-stay which show that bipolar is better. To our knowledge after few studies compare between the techniques according PSA also these studies show weakness in their statistically analysis with no difference between the methods .investigators aim is to study the effect of the operations on PSA levels as an indicator of the quality of resection.

Interventions

PROCEDURETURP

Bipolar and monopolar transurethral resection of the benign prostatic hyperplasia

Sponsors

Assiut University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
SINGLE (Subject)

Eligibility

Sex/Gender
MALE
Age
50 Years to 80 Years
Healthy volunteers
No

Inclusion criteria

* Patients agreeing to participate, clinically fit, age from 50 to 80 years with LUTS related to benign prostate enlargement with no neurological disorder

Exclusion criteria

* Prostate cancer * Previous urethral or prostate surgery * Neurogenic bladder * Urethral stricture * Patient unfit for surgery

Design outcomes

Primary

MeasureTime frameDescription
serum PSA changes after bipolar and monopolar transurethral resection of the benign prostatic hyperplasiawithin one month after interventionTo use PSA levels changes after both techniques (bipolar and monopolar transurethral resection of the benign prostatic hyperplasia)as an indicator of the quality of resection

Secondary

MeasureTime frameDescription
International Prostate Symptom Scorewithin one month after interventionInternational Prostate Symptom Score after bipolar and monopolar transurethral resection of the benign prostatic hyperplasia

Contacts

Primary ContactAndrew H Wahba Gerges, Resident doctor
androwhamam1234@gmail.com+201015349430
Backup ContactMahmoud M Shalaby, professor
shalabymm@aun.edu.eg+201111222203

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026