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The Effect of Exercise on Cognitive Status in Older Adults

Is Aerobic and Dual-task Training Combination the Most Effective Exercise Combination to Improve the Cognitive Status and Physical Function in Older Adults With Mild Cognitive Decline

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05532371
Enrollment
48
Registered
2022-09-08
Start date
2019-01-30
Completion date
2020-02-01
Last updated
2022-09-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Older People

Brief summary

The purpose of the study is to demonstrate the effectiveness of the different combinations of exercises on the cognitive status of older adults with cognitive decline.

Detailed description

This study is planned to examine the effects of combined exercise on cognitive status, lower extremity muscle strength, mobility, physical performance, mood and quality of life in older adults with Mild Cognitive Impairment. Aerobic exercise training and lower limb (extremity) strengthening exercises were applied to the first group, dual-task training and lower limb strengthening exercises were applied to the second group, and aerobic exercise training, dual-task training and lower limb strengthening exercises were applied to the third group.

Interventions

OTHERAerobic exercise training combined with lower limb strengthening

The participants performed aerobic exercise training and lower limb strengthening during this intervention.

OTHERDual-task training combined with lower limb strengthening group (DG)

The participants performed dual-task training combined with lower limb strengthening during this intervention.

OTHERAerobic exercise training combined with dual-task training and lower limb strengthening

The participants performed aerobic exercise training combined with dual-task training and lower limb strengthening during this intervention.

OTHEROnly lower limb strengthening group (CG)

The participants performed only lower limb strengthening group during this intervention.

Sponsors

Muğla Sıtkı Koçman University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Caregiver, Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
65 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Not had a fall in the last six months. * Older adults with an mini mental state examination score between18-23. * Age ≥ 65years.

Exclusion criteria

* having central nervous system pathology that will affect balance * diagnosed with vestibular pathology, * having deformities in the waist, hip, and knee joints, * having lower extremity amputation, * with lower extremity operation history, * malignancy affecting the lower extremity, * having moderate and severe congenital heart disease, coronary heart disease and cerebrovascular disease, * participants who cannot cooperate, * participants who use an assistive walking device, * participants having vision problems.

Design outcomes

Primary

MeasureTime frameDescription
Mini-Mental State Examination12 weeksCognitive status examination is applied with a simple test called Mini-Mental State Examination.
Commander Power Track 2 Manual Tester12 weeksMuscle strength strength is carried out with Commander Power Track 2 Manual Tester.
Timed Up and Go Test12 weeksFunctional mobility is evaluated by Timed Up and Go Test.
Single Leg Stance Test12 weeksStatic balance is evaluated by Single Leg Stance Test
Activities-specific Balance Confidence Scale12 weeksBalance Confidence is evaluated by Activities-specific Balance Confidence Scale.
Six-Minute Walk Test12 weeksExercise capacity is evaluated by Six-Minute Walk Test.
Short Physical Performance Battery12 weeksPhysical performance is evaluated by Short Physical Performance Battery.
Hamilton Depression Rating Scale12 weeksEmotional status is evaluated by Hamilton Depression Rating Scale
World Health Organization Quality of Life-Old module12 weeksQuality of life is evaluated by World Health Organization Quality of Life-Old module

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026