Atrioventricular Nodal Re Entrant Tachycardia, Supraventricular Tachycardia
Conditions
Brief summary
Atrioventricular nodal reentrant tachycardia (AVNRT) is the most common supraventricular tachycardia inducible during an electrophysiological study. Although ablative therapy proved to be the treatment of choice, little is known about the components of the tachycardia circuit. The aim of this study is to detect the presence and patterns of specific electrograms representing slow pathway (SP) potentials and to explore Koch's triangle pattern activation during sinus rhythm and/or atrial extraestimulus with a high-density mapping catheter in an attempt to clarify a fast and safety catheter ablation strategy. We hypothesized that, in patients with dual atrioventricular nodal physiology, during sinus rhythm (SR), high-density mapping (HDM) catheters could identify the SP signals, making possible to delineate small areas of slow conduction associated to abnormal electrograms on Koch's triangle. On a second step, radiofrequency (RF) applications safety guided by the HDM obtained with this method, should interrupt the circuit far from the His region. Finally, SP signals should disappear after the RF procedure when performing a new 3D HDM. A control group of patients without AVN dual physiology should show absence of fragmented/slow conduction zones.
Interventions
DEVICEDescription of Slow pathway signals to facilitate ablation
3D endocardial mapping in order to identify slow pathway signals and abolish or modificate them after radiofrequency ablation
Sponsors
Parc de Salut Mar
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Intervention model description
Single group of intervention. A control group with absence of dual AVN phisiology to check lack of abnormal fragmented/slow conduction confluent zones.
Eligibility
Sex/Gender
ALL
Age
18 Years to 90 Years
Healthy volunteers
No
Inclusion criteria
* Patients \> 18 yo with AVNRT observed after electrophysiological study
Exclusion criteria
* Patients \< 18 yo
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Absence of reinduction of AVNRT after abolition of fragmented/slow conduction signals | one day | Number of patients with absence of fragmented/slow conduction signals observed during sinus rhythm or atrial pacing after radiofrequency application |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Absence of AVNRT relapses | one month | Number of patients with absence of relapses after 1 month of the electrophysiological study |
| Percentage of patient without AVNRT reinduction after procedure | One day | Percentage of patients without tachycardia induction after radiofrequency applications protocol |
Countries
Spain
Outcome results
None listed