Skip to content

Predictive Factors of Graft Detachment Following Dmek

Predictive Factors of Graft Detachment Following Dmek: Retrospective Study About 170 Cases

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05531760
Acronym
PDF DMEKDETACH
Enrollment
170
Registered
2022-09-08
Start date
2022-03-01
Completion date
2022-06-01
Last updated
2022-09-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Descemet Membrane Endothelial Keratoplasty, Fuchs' Endothelial Corneal Dystrophy, Graft Detachment, Pseudophakic Bullous Keratopathy

Brief summary

The aim of this study was to identify the predictive factors of graft detachment after Descemet Membrane Endothelial Keratoplasty (DMEK) surgery. This retrospective study was conducted on patients aged 18 years, with Fuchs' dystrophy (FECD) or pseudophakic bullous keratopathy (PBK), who were scheduled for DMEK or triple-DMEK (combined phacoemulsification and DMEK surgery). Patients with a history of surgery other than cataract surgery were excluded. The study was conducted between 2014 and 2022 and follow-up was for 3 months. The characteristics of patients with and without graft detachment following surgery were compared using logistic regression.

Interventions

Sponsors

Centre Hospitalier Régional Metz-Thionville
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Patients over 18 years of age with DMEK surgery

Exclusion criteria

* all associated eye surgery other than cataract surgery * all existing anterior segment anomalies

Design outcomes

Primary

MeasureTime frameDescription
Appearence of the graft on anterior segment optical coherence tomography (AS OCT) examinationup to 3 months after surgeryclinical examination and anterior segment optical coherence tomography (AS OCT) examination (appearence of the graft)

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026