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Manual Lymphatic Drainage for Rheumatoid Arthritis

The Effect of Manual Lymphatic Drainage on Upper Extremity Functionality in Rheumatoid Arthritis Patients

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05529537
Enrollment
39
Registered
2022-09-07
Start date
2022-08-17
Completion date
2022-10-01
Last updated
2022-12-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Effect of Manual Lymphatic Drainage on Upper Extremity Functionality in Rheumatoid Arthritis

Brief summary

Rheumatoid arthritis (RA) is a chronic, progressive, autoimmune disease characterized by inflammation of the synovial joints and tendon sheaths. As a result of synovitis, progressive damage occurs in cartilage, bone and joints. This damage leads to severe functional limitations and deterioration in quality of life. Synovial tissues are the main site of involvement. Manual lymph drainage reduces the levels of inflammatory mediators associated with edema and pain in the acute phase. On the basis of this concept; Stimulating the lymph system and increasing circulation, removing biochemical residues, regulating sympathetic and parasympathetic system responses, and thus reducing edema and pain. The increase in cardiac parasympathetic activity measured after MLD also contributes to relaxation. In addition to the transport of lymphatic fluid, manual lymph drainage stimulates free nerve endings in the skin with the touches it contains. Gentle stimulation to the skin increases tactile input and closes the pain pathways. In addition, the superficial relaxation and warming provided by soft stimulation creates an effect on the autonomic nervous system and activates the parasympathetic system. The aim of this study is to evaluate the effect of manual lymphatic drainage on upper extremity functionality in individuals with rheumatoid arthritis.

Interventions

OTHERmanual lymphatic drainage

In addition to conventional treatment for 4 weeks, manual lymph drainage will be applied to the patients.

OTHERexcersize

upper extremity normal joint range of motion exercise, strengthening exercise, tendon gliding exercises

Sponsors

Selcuk University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)

Eligibility

Sex/Gender
FEMALE
Age
25 Years to 65 Years
Healthy volunteers
No

Inclusion criteria

* Diagnosed with RA according to ACR criteria * Being between the ages of 18-65 * Volunteering to participate in the study

Exclusion criteria

* Presence of neuromuscular disease * Having difficulty walking * Cognitive impairment * Having systemic disease such as diabetes mellitus and osteoarthritis * History of upper extremity sIf you have Hand Deformity

Design outcomes

Primary

MeasureTime frameDescription
Rheumatoid Arthritis Quality of Life Scale (QOL-RA)10 minutesIn the scale consisting of 30 questions; questions are scored as yes-1 and no-0. The scores obtained range from 0-30, and high scores indicate poor quality of life.
pressure pain threshold5 minutesIt is used for the assessment of sensitivity to pain and the determination of pressure perception. will be evaluated with a digital algometer device with a surface area of 1 cm2 and a sensitivity of 0.25 kg/cm2 (Jtech Medical Industries, ZEVEX Company, USA).
hand grip strength5 minutesThe Jamar hand dynamometer, which is recommended by the American Association of Hand Therapists (AETD) and has high validity and reliability in many studies and is therefore accepted as the gold standard, will be used.
finger grip strength5 minutesFinger pinchmeter (Baseline) will be used to measure finger grip strength.

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026