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Respiratory Complications of Operated Esophageal Atresia in Children

Respiratory Complications of Operated Esophageal Atresia in Children

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05527873
Acronym
ATRESIA
Enrollment
67
Registered
2022-09-06
Start date
2022-03-16
Completion date
2022-12-16
Last updated
2023-11-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Esophageal Atresia

Keywords

esophageal atresia, esophageal malformation, gastroesophageal reflux, asthma, bronchial hyperreactivity

Brief summary

The respiratory complications of esophageal atresia have already been identified. They are mainly related to tracheomalacia linked to the esophageal malformation, and are aggravated by frequently associated gastroesophageal reflux. In this context, symptoms of asthma (or bronchial hyperreactivity) occur more frequently than in the general population and persist into adulthood. Their pathogenesis is still poorly understood and is the subject of much discussion. The therapeutic management of these respiratory complications, poorly codified, remains very heterogeneous from one center to another. In France, the summary of knowledge is updated by the Reference Center for chronic and malformative diseases of the esophagus.

Interventions

None listed

Sponsors

University Hospital, Strasbourg, France
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
1 Years to 12 Years

Inclusion criteria

* Child aged 1 to 12 years old * Child operated on for esophageal atresia between 01/01/2010 and 31/12/2020 and followed up at the University Hospitals of Strasbourg * Child who has not expressed, after being informed, his opposition to the reuse of his data for the purposes of this research * Parental authority having not expressed, after being informed, their opposition to the reuse of their child's data for the purposes of this research.

Exclusion criteria

Subject and/or parental authority having expressed their opposition to participating in the study

Design outcomes

Primary

MeasureTime frame
Retrospective study of respiratory complications of esophageal atresia in childrenFiles analysed retrospectively from January 01, 2010 to December 31, 2020 will be examined

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026