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Benign Thyroid Nodules / Benign Goiter. What Subjective Problems Are Improved With an Operation and Can This be Predicted Preoperatively?

Benign Thyroid Nodules / Benign Goiter. What Subjective Problems Are Improved With an Operation and Can This be Predicted Preoperatively?

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05526261
Enrollment
150
Registered
2022-09-02
Start date
2020-05-30
Completion date
2024-05-30
Last updated
2022-09-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thyroid Nodule

Brief summary

Nodules in the thyroid gland are common. Patients discover these lumps either because of their visible size increase or because of local discomforts such as difficulty swallowing, difficulty breathing or voice changes. The thyroid gland is in close connection with the esophagus, trachea and the vocal nerve. Thus, a lump in the thyroid gland can cause pressure symptoms from these organs. In the event of such complaints, patients are referred for investigation. If it turns out that the patient has a lump in the thyroid gland (goiter), further investigation is carried out with an ultrasound examination and sampling with a needle from the lump (puncture). At present, most thyroid nodules are examined cytologically, ie the thyroid nodules are punctured with a thin needle and the cells that are obtained are analyzed by a cytologist. The material is graded according to Bethesda classification. Higher grading is associated with a higher risk that the tuber is malignant. Lower grading is associated with a lower probability that the tuber can be malignant. If these patients are operated on, it is usually with the hope that their local ailments improve. We want to investigate which patients who have a lump in the thyroid gland and experience pressure problems experience an improvement after a thyroid operation.

Interventions

PROCEDUREHemithyroidectoy

Hemithyroidectomy it is a surgical procedure where half of the thyroid gland is operated.

Sponsors

Linkoeping University
Lead SponsorOTHER_GOV

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* Patients with a thyroid nodule who have local problems and where surgery (hemithyroidectomy) is planned * 18 years or older * Bethesda I-IV

Exclusion criteria

\-

Design outcomes

Primary

MeasureTime frameDescription
Symptom improvementOne year follow uppWhich sypmtoms become better after hemithyroidectomy

Secondary

MeasureTime frameDescription
Comparision of questionnaries2024The patients are going to fill in 4 different questionnaries in 3 different time intervalls. Before the operation, 1 month and 1 year efter the operation.

Countries

Sweden

Contacts

Primary ContactErvin Beka
ervin.beka@regionostergotland.se0738430968

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026