Skin and Connective Tissue Diseases
Conditions
Brief summary
To compare the level of circulating functional mitochondria in the serum of vitiligo patients as compared to controls
Interventions
OTHERNon segmental vitiligo
The subjects will be selected from among those presenting for the consultation or hospitalization of the Dermatology department of the CHU de Nice. All necessary information will be given to the subjects and a briefing note will be given to them. A reflection period will be left for the subjects to sign the informed consent, and if necessary, another appointment will be scheduled for the inclusion visit. The Investigator: * Inform the subject of the goals, constraints and risks of the study and obtain written consent. * Conduct an examination of the subject's medical history Will verify that the subject meets all inclusion criteria and does not present any of the criteria for not including. If the subject consents and they meet all the criteria a 20 ml blood sample will be taken.
OTHERHealth Volunteers
The subjects will be selected from among those presenting for the consultation or hospitalization of the Dermatology department of the CHU de Nice. The family control subjects will be recruited from the vitiligos patients coming into our department. All necessary information will be given to the subjects and a briefing note will be given to them. A reflection period will be left for the subjects to sign the informed consent, and if necessary, another appointment will be scheduled for the inclusion visit. The Investigator: * Inform the subject of the goals, constraints and risks of the study and obtain written consent. * Conduct an examination of the subject's medical history Will verify that the subject meets all inclusion criteria and does not present any of the criteria for not including. If the subject consents and they meet all the criteria a 20 ml blood sample will be taken.
Sponsors
Centre Hospitalier Universitaire de Nice
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
NONE
Intervention model description
Patients with non segmental vitiligo compared to healthy volunteers (1st degree family of vitiligo patients) atopic dermatitis, psoriasis and alopecia areata patients
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
Yes
Inclusion criteria
* Patients with non segmental vitiligo, * atopic dermatitis, psoriais, alopecia areata, * 1st degree relative of vitiligo patients.
Exclusion criteria
* segmental or mixed vitiligo, * personnal history of other autoimmune disorders, * oral use of antioxidant, * pregant women
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Total number of circulating functionnal mitochondria (CFM) in the plasma | at baseline | Level of CFM in vitiligo serum as compared to controls |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| measuring the functionality of circulating mitochondria | At baseline | Functional analysis of CFM in vitiligo patients as compared to controls analyzed by MFI Mito Tracker |
Countries
France
Outcome results
None listed