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Integrative Study of Vestibular Pathology

Integrative Study of Vestibular Pathology With Analysis of Postural, Neurosensory, and Cognitive Disorders: Search for New Markers on the Causes and Consequences of Vertigo

Status
Recruiting
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05525728
Acronym
SENSORIEL2
Enrollment
80
Registered
2022-09-02
Start date
2022-06-18
Completion date
2026-01-31
Last updated
2022-09-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dizziness; Syndrome

Keywords

posture, vertigo, cognition, emotion, physiotherapist, vestibular system, balance

Brief summary

Exploratory posturological, neurosensory, cognitive, emotional, personality and general evaluations (quality of life). The investigators will characterize a sensory profile quantified by one or more scores from a multi-parameter baysian approach. Each parameter and these scores will be correlated to the type of vestibular damage and its recovery in order to establish diagnostic, prognostic and therapeutic follow-up markers.

Detailed description

This is an exploratory neurophysiological work that aims to identify diagnostic, prognostic and therapeutic markers in vestibular pathology. Theinvestigators wish to characterize the neurosensory profile of individuals using new exploration paradigms provided by a new posturology platform coupled with virtual reality scenarios and by proposing a complete transversal approach in terms of evaluation of the subjects: personality, cognition, emotion including the depressive state, sensory strategy, general data. Baysian statistical approaches and linear mixed model will be used to determine markers of sensory profile correlated to the vestibular damage for diagnostic, prognostic and therapeutic follow-up. The investigators aim to be able to better characterize the cognitive-emotional and sensory deficits expressed by the vertiginous and unstable patients, to integrate it into the evaluation of the vestibular pathology, to use these markers to better discriminate the underlying physiopathological mechanisms, and to improve at the same time the diagnosis of the functional attack and the rehabilitation follow-up of the patients.

Interventions

OTHERNeurosensory

Physiological and neurophysiological investigations

Sponsors

University Hospital, Caen
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE

Intervention model description

a group of patient suffering from vestibular pathology will be investigated regardless the etiology of the vertigo or dizziness

Eligibility

Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No

Inclusion criteria

* Male or female patient (18-80 years old) * Patient with an acute or chronic vestibular pathology according to ENT diagnostic criteria

Exclusion criteria

* Subjects under 18 years of age * Pregnant or breastfeeding women, * Persons in an emergency situation or unable to give their consent, including adults under guardianship * Person under legal protection * Patient presenting a vertigo or postural disorders of non vestibular etiology * Persons deprived of liberty, minors, protected adults, * Patients with an intercurrent neurological pathology including cerebellar pathology * Inclusion of the subject in another interventional research protocol with pharmacological aim during the present study

Design outcomes

Primary

MeasureTime frameDescription
Posturethrough follow-up, an average of 6 monthspostural measurement
Cognitionthrough follow-up, an average of 6 monthsSpatial cognitive performance in a calibrated virtual radial maze
Personnality characteristicthrough follow-up, an average of 6 monthsEvaluation of the BIg Five inventory test
Sleepthrough follow-up, an average of 6 monthsQuantitative sleep recording
Emotionthrough follow-up, an average of 6 monthsAnxiety measurement via questionnary

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026