Carotid Artery Plaque, Carotid Stenosis, Stent Embolisation
Conditions
Keywords
carotid artery stenosis, vulnerable plague, carotid stenting
Brief summary
To investigate the efficacy and safety of carotid stenting for vulnerable carotid plaques. All patients with carotid artery stenosis underwent carotid arterial contrast-enhanced ultrasonography before operation. According to the examination results, they were divided into two groups: vulnerable plaque group and stable plaque group. The incidence of perioperative stroke events in the two groups was compared. The incidence of stroke events in the two groups within 1 year was compared.
Detailed description
1. To enroll 100 cases of patients suffering from carotid artery stenosis。the investigators perform contrast enhanced ultrasound on patients for identifying the vulnerable plagues 2. The investigators divide patients into the stable group and the vulnerable group based on the results of CEUS inspection. 3. All patients undergo carotid stent. To analysis the incidence of postoperative complications such as stroke and mortality within 30 days and to compare the differences between the two groups.
Interventions
PROCEDUREcarotid artery stenting
Implantation of stents at the site of carotid artery stenosis for the treatment of carotid plaque with severe stenosis
Sponsors
Beijing Tsinghua Chang Gung Hospital
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
20 Years to 90 Years
Healthy volunteers
No
Inclusion criteria
* The patients with ischemic symptom whose carotid stenosis were more than 50% * The patients without ischemic symptom whose carotid stenosis were more than 70%
Exclusion criteria
* • Confirmed with severe intracranial vascular lesions * Suffering from the large area cerebral infarction or critical stroke sequela * Restenosis after CEA or CAS * Suffering from severe coronary heart disease, respiratory failure,the hypertension difficult to controled * Patients with malignant tumor or expected life \< 2 years
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Perioperative 30-day stroke rate | 30 days | To determine whether there is a new cerebral infarction by postoperative re-examination of brain MRI and preoperative brain MRI |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| 1-year stroke rate after surgery | 1 year | Stroke rate in ipsilateral carotid artery blood supply area within 1 year after operation |
Countries
China
Contacts
Primary Contactkeqiang zhao, M.D.
Backup Contactweiwei wu, M.D.
Outcome results
None listed