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Pulse Momentum Research in Pulse Diagnosis

Quantitative Research on Pulse Momentum in Pulse Diagnosis of Traditional Chinese Medicine

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05522413
Enrollment
100
Registered
2022-08-31
Start date
2022-08-10
Completion date
2023-07-10
Last updated
2022-08-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Suboptimal Health Status

Keywords

discrete wavelet transformation, Pulse diagnosis in TCM

Brief summary

Traditional Chinese medicine has a long history of disease diagnosis applications by pulse diagnosis. The pulse position, number, shape, and momentum can be used as four guidelines for pulse classification. However, the finger feeling is difficult to be expressed in a quantitative approach for clinical teaching and illness-state recognition. The pressure sensor was applied to measure wrist pulse waveforms for analysis. In this research project, the discrete wavelet transformation (DWT) is used to decompose the time-domain pulse into several sets of signals, which are allocated at different frequency bands. The high-frequency signal over the range of 12-50 Hz is then acquired to calculate the spectral energy ratio (SER) for quantization of the pulse momentum to the persons under the suboptimal health status (SHS).

Detailed description

Traditional Chinese medicine has a long history of disease diagnosis applications by pulse diagnosis. Ancient physicians classified the pulse types on the basis of pulse manifestation attributes and finger-feeling features. The pulse position, number, shape, and momentum can be used as four guidelines for pulse classification. However, the finger feeling is difficult to be expressed in a quantitative approach for clinical teaching and illness-state recognition. The modernization of pulse diagnosis in Taiwan began in the 1970s. The pressure sensor was applied to measure wrist pulse waveforms for analysis. Nowadays, the pulse position, number, and shape have been quantitatively analyzed and classified by using time-domain pulse signals and their corresponding frequency spectrums. However, since it is lack of effective high-frequency pulse acquisition method and quantitative approach, the quantitative research on pulse momentum for judgement of pathological status is still being investigated. In this research project, the discrete wavelet transformation (DWT) is used to decompose the time-domain pulse into several sets of signals, which are allocated at different frequency bands. The high-frequency signal over the range of 12-50 Hz is then acquired to calculate the spectral energy ratio (SER) for quantization of the pulse momentum. In addition, the approximate entropy (ApEn) of the high-frequency signal is computed and defined as a new quantitative factor of pulse momentum. It will be further tried to relate the scores of clinical questionnaires. The analysis method proposed in this project has been preliminarily applied to analyze the pulse waveforms of the persons under the suboptimal health status (SHS) to demonstrate the effectiveness. In the future, more measured pulses of the subject under test will be collected and analyzed to examine the robustness of the proposed method. It is also planned to figure out the relationship between the quantitative factors, such as SER and ApEn, and the high- and low-frequency parameters of the heart rate variability (HRV). It can be further linked to the activation of sympathetic and parasympathetic nerves, and potentially build up an objective bridge of clinical diagnosis to connect the traditional Chinese medicine and modern western medicine.

Interventions

None listed

Sponsors

National Yang Ming Chiao Tung University
CollaboratorOTHER
Taipei Veterans General Hospital, Taiwan
Lead SponsorOTHER_GOV

Study design

Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
20 Years to 70 Years
Healthy volunteers
Yes

Inclusion criteria

* A+B+C or A+B+D that meet the following description, and those who have no clear diagnosis of chronic diseases by western medicine, can be included: (A) Sub-Health Questionnaire (SHSQ-25) ≧35 points (B) Resting blood pressure 120-139/80-89 mmHg measured more than 3 times a week (C) The PSQI score of the sleep questionnaire on the first test is greater than 5 points (D) Body mass index (BMI): 24\ 29 Kg/m2

Exclusion criteria

* Considerations for selection/

Design outcomes

Primary

MeasureTime frameDescription
Pulse diagnosis data analysis1 dayPalpation of the 6 pulse positions (right cun, right guan, right chi, left cun, left guan, left chi) measured by the pulse diagnostic instrument are read into the processing program, and then the time domain signal of each pulse position is analyzed in sequence .

Secondary

MeasureTime frameDescription
Suboptimal health status questionnaires1 day25 items of Suboptimal symptoms

Countries

Taiwan

Contacts

Primary ContactYen-Ying KUNG, doctor
yykung@vghtpe.gov.tw886-2-28757453
Backup ContactChao-Hsiung Tseng, doctor
chtseng@mail.ntust.edu.tw886-2-27376416

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026