Impact of EUS Guided Treatment of Gastric Varices

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05521685

Enrollment

119

Registered

2022-08-30

Start date

2022-04-19

Completion date

2023-05-22

Last updated

2024-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastric Varices Bleeding

Brief summary

The purpose of the study is to determine the clinical impact of cyanoacrylate tissue adhesive treatment for Gastric Varices performed by Indiana University EUS physicians.

Detailed description

Using an IRB approved database (IU IRB#1209009522; NCT02037659), data collected from the database will be evaluated to identify complications, risk of rebleeding, death within 1 year of treatment, varices eradication and need for re-intervention associated with cyanoacrylate tissue adhesive (Dermabond) treatment performed by Indiana University Endoscopic Ultrasound (EUS) physicians.

Interventions

PROCEDUREEndoscopic Ultrasound (EUS) administration of cyanoacrylate tissue adhesive to control bleeding gastric varices

Subjects will have undergone treatment and been enrolled into the existing registry.

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 99 Years

Healthy volunteers

Inclusion criteria

* Any subject enrolled into the existing database (IU IRB#1209009522; NCT02037659).

Exclusion criteria

* Not enrolled into the database.

Design outcomes

Primary

Measure	Time frame	Description
Impact of EUS guided treatment of Gastric varices post procedure complications and adverse events	Complications reviewed at time of retrospective study. EUS-guided sclerotherapy done between November 2012 and December 2021	Retrospective data review to Determine post procedure complications and adverse events at 24h, between 2 and 7 days and between 8 and 30 days after the procedure. Additionally, tracking rebleeding after first and second EUS. Moreover, looking at eradication of GV rate on second endoscopy (considered eradicated if absent or if residual varices have no or minimal flow on doppler)eradication, and need for re-intervention following cyanoacrylate tissue adhesive treatment for Gastric Varices performed by IU EUS physicians.

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026