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Feasibility and Acceptability of the Cannabis Awareness and Prevention Toolkit

Feasibility and Acceptability of the Cannabis Awareness and Prevention Toolkit

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05521321
Enrollment
658
Registered
2022-08-30
Start date
2022-10-01
Completion date
2025-05-16
Last updated
2026-07-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cannabis Use

Keywords

youth, cannabis, education, health, prevention, marijuana

Brief summary

The Stanford Smart Talk Cannabis Awareness and Prevention Curriculum includes 5 lessons, each providing activities, online quiz games, and worksheets in addition to presentations, resources, and other materials aimed at addressing key factors associated with youth cannabis use, including changing adolescents' attitudes towards and misperceptions about cannabis; increasing their refusal skills to pulls of marketing and social media; reducing stress and depression which have been linked to cannabis initiation and use; improving coping skills; and decreasing intentions and actual use of all cannabis products. The aim of this study is to investigate the extent to which the curriculum changes students' intentions to use and actual use of cannabis.

Interventions

BEHAVIORALStanford Smart Talk Cannabis Awareness and Prevention curriculum

Stanford Cannabis Awareness and Prevention curriculum delivered as a 5-session curriculum administered in a school classroom setting.

Sponsors

Stanford University
Lead SponsorOTHER
National Institute on Drug Abuse (NIDA)
CollaboratorNIH

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
10 Years to 20 Years
Healthy volunteers
Yes

Inclusion criteria

* Middle school and high school students receiving health education at schools participating in the study

Exclusion criteria

\-

Design outcomes

Primary

MeasureTime frameDescription
Cannabis Use (Lifetime)Baseline, Post-intervention (approx. 3 days post-baseline), and 6-month Follow-upInvestigator-originated survey measures (questions) assess lifetime cannabis use. This outcome measure assesses cannabis use.
Cannabis Use (Past 30 Days)Baseline, Post-intervention (approx. 3 days post-baseline), and 6-month Follow-upInvestigator-originated survey measures (questions) assess cannabis use in the past 30 days.
Intention to Use Cannabis in the Future - Smoked CannabisBaseline, Post-intervention (approx. 3 days post-baseline), and 6-month Follow-upInvestigator-originated survey measures (questions) assessing participant intention to use cannabis in the future. Assessed on a Likert-scale (1 - Definitely not, 4 - Definitely yes).
Intention to Use Cannabis in the Future - Vaped CannabisBaseline, Post-intervention (approx. 3 days post-baseline), and 6-month Follow-upInvestigator-originated survey measures (questions) assessing participant intention to use cannabis in the future. Assessed on a Likert-scale (1 - Definitely not, 4 - Definitely yes).
Intention to Use Cannabis in the Future - Cannabis EdiblesBaseline, Post-intervention (approx. 3 days post-baseline), and 6-month Follow-upInvestigator-originated survey measures (questions) assessing participant intention to use cannabis in the future. Assessed on a Likert-scale (1 - Definitely not, 4 - Definitely yes).

Secondary

MeasureTime frameDescription
Cannabis KnowledgeBaseline and Post-intervention (approx. 3 days post-baseline)Participants were asked 13 questions related to their knowledge of cannabis, resulting in an overall scale of 0 to 13, higher scores indicated greater knowledge.
Perceived Addictiveness and Harmfulness - Smoked CannabisBaseline, Post-intervention (approx. 3 days post-baseline), and 6-month Follow-upInvestigator-originated survey measures (questions) assessing participants' perceptions of cannabis addiction and harm. Assessed on a Likert-scale (1 - Not at all addictive/harmful, 5 - Extremely addictive/harmful).
Perceived Addictiveness and Harmfulness - Vaped CannabisBaseline, Post-intervention (approx. 3 days post-baseline), and 6-month Follow-upInvestigator-originated survey measures (questions) assessing participants' perceptions of cannabis addiction and harm. Assessed on a Likert-scale (1 - Not at all addictive/harmful, 5 - Extremely addictive/harmful).
Perceived Addictiveness and Harmfulness - Cannabis EdiblesBaseline, Post-intervention (approx. 3 days post-baseline), and 6-month Follow-upInvestigator-originated survey measures (questions) assessing participants' perceptions of cannabis addiction and harm. Assessed on a Likert-scale (1 - Not at all addictive/harmful, 5 - Extremely addictive/harmful).

Countries

United States

Contacts

PRINCIPAL_INVESTIGATORBonnie Halpern-Felsher, Ph.D.

Stanford University

Participant flow

Pre-assignment details

19 schools were assessed for eligibility. 11 were randomized to intervention or standard of care. Educators were considered to be enrolled only at those schools that received the intervention (they delivered the intervention to the students, and participated in post-intervention qualitative interviews focused on quality assurance and quality improvement).

Baseline characteristics

Characteristic
Age, Continuous14.0 years
STANDARD_DEVIATION 0.8
Ethnicity (NIH/OMB)
Hispanic or Latino
18 Participants
Ethnicity (NIH/OMB)
Not Hispanic or Latino
115 Participants
Ethnicity (NIH/OMB)
Unknown or Not Reported
4 Participants
Race (NIH/OMB)
American Indian or Alaska Native
1 Participants
Race (NIH/OMB)
Asian
51 Participants
Race (NIH/OMB)
Black or African American
19 Participants
Race (NIH/OMB)
More than one race
26 Participants
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
1 Participants
Race (NIH/OMB)
Unknown or Not Reported
7 Participants
Race (NIH/OMB)
White
95 Participants
Region of Enrollment
United States
425 Participants
Sex/Gender, Customized
Man
78 Participants
Sex/Gender, Customized
Non-binary/Gender Diverse
9 Participants
Sex/Gender, Customized
Unknown/Not Reported
1 Participants
Sex/Gender, Customized
Woman
70 Participants

Adverse events

Event typeEG000
affected / at risk
EG001
affected / at risk
deaths
Total, all-cause mortality
0 / 4190 / 239
other
Total, other adverse events
0 / 4190 / 239
serious
Total, serious adverse events
0 / 4190 / 239

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jul 29, 2026