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Correlates Between EEG Microstates and Clinical Characteristics of People With Stroke

Correlates Between EEG Microstates and Clinical Characteristics of People With Stroke

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05519631
Enrollment
45
Registered
2022-08-29
Start date
2023-01-30
Completion date
2023-09-20
Last updated
2023-05-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Electroencephalogram, Stroke

Brief summary

Stroke has been considered one of the main causes of long-term disability in the adult population, and is no longer considered a disease of the elderly, since 2/3 of all strokes occur among people under 70 years of age. According to the Ministry of Health, stroke is responsible for 40% of early retirements, being one of the most important causes of mortality in Brazil. The electroencephalogram (EEG) has been shown to be a very useful tool in the study of functional status and for the diagnosis of brain damage and disorders. It is considered a simple, non-invasive test with high temporal resolution, being a method widely used in laboratories to non-invasively monitor brain activity.

Detailed description

Stroke has been considered one of the main causes of long-term disability in the adult population, and is no longer considered a disease of the elderly, since 2/3 of all strokes occur among people under 70 years of age. According to the Ministry of Health, stroke is responsible for 40% of early retirements, being one of the most important causes of mortality in Brazil. Stroke usually causes long-term deficits such as asymmetrical muscle weakness between limbs, impaired proprioceptive ability, sensory loss, vision problems, and spasticity. In addition, these sensorimotor deficits interfere with various functions of the lower limbs, including balance, postural control, and gait ability, affecting their quality of life. The electroencephalogram (EEG) has been shown to be a very useful tool in the study of functional status and for the diagnosis of brain damage and disorders. It is considered a simple, non-invasive test with high temporal resolution, being a method widely used in laboratories to non-invasively monitor brain activity. Microstates reflect short periods (\ 100 ms) of nearly stable brain states evolving over time, resulting from the synchronous and coordinated activity of brain networks. The aim of this study is to observe whether EEG microstates have correlations with clinical characteristics of people with stroke.

Interventions

OTHERelectroencephalogram

The EEG is the recording of electrical activity in the brain in different regions of the cortex. The capture of electrical signals is performed by attaching electrodes to the surface of the scalp. As the EEG signal has an amplitude in microvolts (µVpp) it is necessary to use amplifiers, leaving the signal possible to be registered. The electrode-electrolyte interface is very important and must be able to provide a good connection between the skin and the conductive material of the electrode, otherwise the EEG signal, in addition to being contaminated by noise, may suffer distortion.

Sponsors

Federal University of Paraíba
Lead SponsorOTHER

Study design

Observational model
OTHER
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* people over 18 years of age, regardless of sex and with a stroke confirmed by computed tomography or magnetic resonance imaging.

Exclusion criteria

* have other associated neurological pathology

Design outcomes

Primary

MeasureTime frameDescription
eeg microstatesImmediately after evaluationWe will determine the number of topographic maps using a pre-determined criterion of the four classical maps (A, B, C and D) and classify the continuous EEG data according to the topographic map with which a given stretch has the highest correlation.

Secondary

MeasureTime frameDescription
Relationship between microstates and injury severityImmediately after evaluationThey were evaluated with the National Institute of Health Stroke Scale (NIHSS) to quantify the severity and magnitude of the neurological deficit after the stroke.
Relationship between microstates and cognitive functionImmediately after evaluationassessment of cognitive function - Montreal Cognitive Assessment (MoCA)

Countries

Brazil

Contacts

Primary ContactLETICIA MARIA
leticiamaria.fisio@gmail.com81 993684588

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026