Cardiopulmonary, Congenital Heart Disease in Children, Infant Conditions, Infant Development, Motor Delay, Motor Neuropathy
Conditions
Keywords
infant, rehab management APP, home-based exercise, cardiopulmonary endurance, motor developmental level
Brief summary
In this single-center, randomized controlled trial, patients (4-8 months) with CHD were randomly assigned to either a recovery group (home-based rehab exercise periodically) supervised by cellphone APP or to a control group. Left ventricular ejection fractions (LVEF), the rate of increase in heart rate (rHRI), and the rate of recovery heart rate (rHRR) were measured for representing cardiopulmonary capacity. The Alberta test and Neuro-intelligence Scale were used to evaluate their motor developmental outcomes. This study verified the feasibility of this rehab method and indicated that 6-month home-based exercise training can improve cardiopulmonary endurance and motor developmental level in infant CHD patients.
Interventions
BEHAVIORALexercise-guidance on rehab APP
Training motions included sitting balance, hand support, crawling and squatting training12-14 were scheduled for 1 to 3 months postoperatively, moreover, climbing over obstacles was for 3 to 6 months.
Sponsors
Gejingwa Zhao
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
4 Months to 8 Months
Healthy volunteers
No
Inclusion criteria
* CHD infants (aged 4-8 months) with atrial septum defect (ASD) or ventricular septum defect (VSD)
Exclusion criteria
* chromosomal abnormalities; family history of mental retardation; small for gestational age and prematurity; history of perinatal asphyxia and hyperbilirubinemia; history of central nervous system disease or imaging suggestive of brain dysplasia
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Baseline LVEF | pre-operative for baseline assessment | Left ventricular ejection fraction before surgery |
| Baseline rHRI | pre-operative for baseline assessment | The rate of increase in heart rate before surgery |
| Baseline rHRR | pre-operative for baseline assessment | The rate of recovery heart rate before surgery |
| Baseline Alberta score | pre-operative for baseline assessment | Alberta motor test results before surgery |
| Baseline Neuro-intelligence Scale | pre-operative for baseline assessment | Developmental Quotient (DQ) before surgery |
| LVEF one month after the surgery | one month after surgery | Left ventricular ejection fraction one month after the surgery |
| rHRI one month after the surgery rHRI one month after the surgery | one month after surgery | The rate of increase in heart rate one month after the surgery |
| rHRR one month after the surgery | one month after surgery | The rate of recovery heart rate one month after the surgery |
| Alberta score one month after the surgery | one month after surgery | Alberta motor test results one month after the surgery |
| Neuro-intelligence Scale one month after the surgery | one month after surgery | Developmental Quotient (DQ) one month after the surgery |
| LVEF three months after the surgery | three months after surgery | Left ventricular ejection fraction three months after the surgery |
| rHRI three months after the surgery | three months after surgery | The rate of increase in heart rate three months after the surgery |
| rHRR three months after the surgery | three months after surgery | The rate of recovery heart rate three months after the surgery |
| Alberta score three months after the surgery | three months after surgery | Alberta motor test results three months after the surgery |
| Neuro-intelligence Scale three months after the surgery | three months after surgery | Developmental Quotient (DQ) three months after the surgery |
| LVEF six months after the surgery | six months after surgery | Left ventricular ejection fraction six months after the surgery |
| rHRI six months after the surgery | six months after surgery | The rate of increase in heart rate six months after the surgery |
| rHRR six months after the surgery | six months after surgery | The rate of recovery heart rate six months after the surgery |
| Alberta score six months after the surgery | six months after surgery | Alberta motor test results six months after the surgery |
| Neuro-intelligence Scale six months after the surgery | six months after surgery | Developmental Quotient (DQ) six months after the surgery |
Countries
China
Outcome results
None listed