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Inspiratory Muscle Training, Autonomic Dysfunction and Blood Pressure

Effect of Interval Inspiratory Muscle Training on Autonomic Dysfunction and Blood Pressure in Hypertensive Adults: A Randomized Controlled Trial

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05517915
Enrollment
28
Registered
2022-08-26
Start date
2018-01-08
Completion date
2018-08-27
Last updated
2022-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypertension

Keywords

Interval Inspiratory Muscle Training, Hypertension, Autonomic Dysfunction, Blood Pressure

Brief summary

This study finds the effectiveness of inspiratory muscle threshold loading training among adults with hypertension. A sample of hypertensive subjects was divided into two groups - inspiratory muscle training (IMT) - group (inspiratory muscle training was prescribed) and sham-group (no load was prescribed during IMT). Both groups had training sessions comprising seven cycles of two minutes bouts of breathing counter to an inspiratory load, each bout parted by one minute of unloaded recovery. Treatment session was performed for three times per week for a total of six weeks. Measurement of each of the variables (blood pressure, resting heart rate (RHR), heart rate variability (HRV)) was taken at baseline and after the six-week intervention.

Detailed description

The present study aimed to examine the outcome of interval inspiratory muscle training at 70% load on blood pressure, resting heart rate and autonomic dysfunction in the hypertensive adults. Participants were divided into two groups: IMT and sham. In IMT group, the threshold loading inspiratory muscle trainer from POWERbreathe was used with 70% IMT threshold. In Sham group, IMT was unloaded.

Interventions

Interval inspiratory muscle training was performed using the inspiratory muscle trainer.

OTHERSham inspiratory muscle training.

Interval inspiratory muscle training was performed using the unloaded inspiratory muscle trainer.

Sponsors

King Saud University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)

Masking description

Outcome assessor was kept blind to the allocation of participants.

Intervention model description

Two group pretest-posttest parallel design.

Eligibility

Sex/Gender
ALL
Age
30 Years to 65 Years
Healthy volunteers
No

Inclusion criteria

* stage 1 hypertension * essential hypertension * mild hypertension

Exclusion criteria

* Subjects participating in exercise training for more than the last six months * severe musculoskeletal limitations * severe neurological limitations * cognitive impairments * uncontrolled diabetes * uncontrolled hypertension * a history of myocardial infarction (MI) * a history of stroke in the last six months * unstable angina * chronic heart failure * pulmonary disease of any etiology

Design outcomes

Primary

MeasureTime frameDescription
Resting heart rate6 weeksResting heart rate was measured at baseline and after completion of intervention.
Autonomic functions6 weeksAutonomic functions were assessed by measuring the heart rate variability parameters at baseline and after completion of intervention.
Blood pressure6 weeksSystolic and diastolic blood pressures were measured at baseline and after completion of intervention.

Countries

Saudi Arabia

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026