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Lymphovascular Abnormalities Under Tattoos

Lymphovascular Abnormalities Under Tattoos : Preliminary Reports of One Observational Study

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05515146
Enrollment
19
Registered
2022-08-25
Start date
2021-12-01
Completion date
2022-01-31
Last updated
2022-08-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tattoo

Keywords

lymphatic vessels, indocyanin green, near infra red fluorescence lymphatic imaging, tattoo

Brief summary

The number of tattooed people is increasing and some complications secondary to tattoos suggest that the lymphatic vascular system might be implicated in their pathogenesis. Abnormalities have been described at the level of the lymph nodes draining the tattooed areas but nothing was reported about the lymphatic vessels under tattoos. This is the aim of the present work.

Detailed description

19 subjects with 20 tattooed skin surfaces were enrolled after written informed consent and the lymphvascular drainage under the tattooed surface was studied using one near infrared camera device after one intradermal injection of Indocyanine Green.

Interventions

DIAGNOSTIC_TESTnear infra red fluorescence lymphatic imaging

ICG (0.2 ml from 25mg of ICG diluted by 5.0 ml of aqua ad injectabilia) was injected intradermally at the basis of the tattooed cutaneous area and at one point chosen so that the tracer had to flow under this area directly towards the root of the limb

Sponsors

Haute Ecole Bruxelles-Brabant
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 40 Years

Inclusion criteria

* presence of one tattoo at the level of one limb * written informed consent

Exclusion criteria

1. History of iodine allergy or anaphylactic reactions to insect bites or medication; 2. Hyperthyroidism; 3. Severe cardiac or pulmonary disease; 4. Significant renal failure (creatinine \> 400 μmol/l); 5. Pregnancy; 6. any known disease of the skin (such as psoriasis); 7. any disease known to affect the cutaneous tissues (such as diabetes); 8. any previous operation and/or trauma at the level of tattooed limb; 9. familial history of lower limb edemas: 10. skin infection after the tattoo

Design outcomes

Primary

MeasureTime frameDescription
normal or abnormal lympho-vascular drainageimagings were performed directly after the injection (duration 3 minutes)The following pictures were considered as normal \- lymphatic vessels are well seen and drainage is fast spontaneously

Countries

Belgium

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026